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Uncategorized Published - 26 March, 2015    By - Dr Clemens
Anesthetic management of patients with Joubert syndrome: a retrospective analysis of a single-institutional case series

Published in Paediatr Anaesth. 2014 Nov;24(11):1180-4. Authors: Sriganesh K et al OBJECTIVE: To analyze the anesthetic techniques used for sedation during magnetic resonance imaging (MRI) study of patients with Joubert syndrome (JS) and assess the safety and efficacy of these anesthetic regimens in these children. BACKGROUND: Joubert syndrome is a rare neurological disorder with significant anesthetic […]

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Uncategorized Published - 26 March, 2015    By - Dr Clemens
Perioperative respiratory complications following awake and deep extubation in children undergoing adenotonsillectomy

Published in Paediatr Anaesth. 2015 Apr;25(4):392-9 Authors: Baijal RG et al BACKGROUND: Perioperative respiratory complications after adenotonsillectomy (T&A) are common and have been described to occur more frequently in children below 3 years of age, those with cranio-facial abnormalities, Down syndrome, obstructive sleep apnea, morbid obesity, and failure to thrive. AIMS: To investigate the association between awake […]

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Uncategorized Published - 26 March, 2015    By - Dr Clemens
Unintentional epidural injection of 88 μg·kg(-1) of epinephrine

Published in Paediatr Anaesth. 2014 Nov;24(11):1185-7 Authors: August DA et al We report the effects of 88 μg·kg(-1) of epinephrine (1:10,000) injected into the caudal epidural space of a 42-week postconceptual age infant. No long-term neurological or cardiovascular sequelae occurred. Noninvasive cardiac output (CO) monitoring revealed increased CO, contractility, and stroke volume for about an hour, […]

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Uncategorized Published - 25 March, 2015    By - Dr Clemens
Does Carotid Artery Stenosis Predict Perioperative Stroke After Noncardiac Surge

Published in Anesthesiology 2014 Nov. Authors: Sonny A et al. A retrospective study suggests no association. Does carotid artery stenosis predispose patients who undergo noncardiac, noncarotid surgery to perioperative stroke? To find out, Cleveland Clinic researchers performed this retrospective study. During a 5-year period, 2110 patients who underwent noncardiac surgery had carotid duplex ultrasonography performed within […]

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Uncategorized Published - 25 March, 2015    By - Dr Clemens
Emergence agitation after orthognathic surgery: a randomised controlled comparison between sevoflurane and desflurane.

Published in Acta Anaesthesiol Scand. 2015 Feb;59(2):224-31 Authors: Choi GJ et al BACKGROUND: This study aimed to compare emergence agitation following sevoflurane and desflurane anaesthesia in adults undergoing orthognathic surgery. The hypothesis was that there might be a difference in the incidence of emergence agitation following sevoflurane and desflurane anaesthesia considering the difference in blood solubility […]

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Uncategorized Published - 25 March, 2015    By - Dr Clemens
Disruption of cortical connectivity during remifentanil administration is associated with cognitive impairment but not with analgesia

Published in Anesthesiology. 2015 Jan;122(1):140-9 Authors: Khodayari-Rostamabad A et al BACKGROUND: The authors investigated the effect of remifentanil administration on resting electroencephalography functional connectivity and its relationship to cognitive function and analgesia in healthy volunteers. METHODS: Twenty-one healthy male adult subjects were enrolled in this placebo-controlled double-blind cross-over study. For each subject, 2.5 min of multichannel […]

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Uncategorized Published - 25 March, 2015    By - Dr Clemens
Chondroitin Sulfate Plus Glucosamine Comparable to Celecoxib for Knee Osteoarthritis Pain

Chondroitin sulfate plus glucosamine is comparable to celecoxib in reducing pain in patients with knee osteoarthritis and is a safe alternative for patients with cardiovascular or gastrointestinal conditions who have contraindications to celecoxib. The findings were presented here at the 2014 Annual Scientific Meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals (ACR/ARHP) […]

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Uncategorized Published - 25 March, 2015    By - Dr Clemens
The addition of tramadol to the standard of i.v. acetaminophen and morphine infusion for postoperative analgesia in neonates offers no clinical benefit: a randomized placebo-controlled trial

Published in Paediatr Anaesth. 2014 Nov;24(11):1149-57 Authors: Olischar M et al BACKGROUND: Tramadol is used following neonatal cardiac and general surgery. However, its ability to opioid-spare or facilitate earlier extubation in postoperative neonates is unquantified. OBJECTIVE: This randomized placebo-controlled trial aimed to assess whether tramadol’s addition to standard analgesia resulted in earlier extubation or reduced analgesic/sedative […]

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Uncategorized Published - 24 March, 2015    By - Dr Clemens
Grass-green urine from propofol infusion.

Published in Acta Anaesthesiol Scand. 2015 Feb;59(2):265-7. Authors: Pedersen AB et al Green urine from propofol infusion is a benign and rare side effect. The discolouration appears when clearance of propofol exceeds hepatic elimination, and extrahepatic elimination of propofol occurs. This case report presents a 24-year-old male with grass green discolouration of urine based on propofol […]

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Uncategorized Published - 24 March, 2015    By - Dr Clemens
FDA Approves Extended-Release Hydrocodone Product With Abuse-Deterrent Properties

The US Food and Drug Administration (FDA) has approved extended-release hydrocodone bitartrate (Hysingla ER), an opioid analgesic to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Hydrocodone bitartrate ER has properties that are expected to reduce, but not totally prevent, abuse of the drug […]

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