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Uncategorized Published - 10 June, 2015    By - Dr Clemens
A Confounding Coincidence: Epidural Anesthesia and Paraplegia Due to Intramedullary Tuberculoma in a Patient who Underwent Cholecystectomy

Authors: Changyi Wu et al Published in BMC Anesthesiol. 2014;14(100) Background Paraplegia associated with epidural anesthesia or caused by intramedullary spinal tuberculoma is rare but catastrophic. We present a case of paraplegia following epidural anesthesia in a patient with an undiagnosed intramedullary spinal tuberculoma. Case presentation A 42-year-old man developed paraplegia after an open cholecystectomy under epidural anesthesia. […]

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Uncategorized Published - 9 June, 2015    By - Dr Clemens
Stepped-Care Approach to Chronic Pain Improves Function

A two-step strategy to managing chronic pain in US military veterans was associated with improved function and decreased pain severity, yielding a 30% improvement in pain-related disability, a new study shos. Step 1 included 12 weeks of analgesic treatment and optimization according to an algorithm, coupled with pain self-management strategies. Step 2 comprised 12 weeks […]

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Uncategorized Published - 9 June, 2015    By - Dr Clemens
GlideScope Use Improves Intubation Success Rates

An Observational Study Using Propensity Score Matching Published in BMC Anesthesiol. 2014;14(101) Authors: James W Ibinson et al Background Rigid video laryngoscopes are popular alternatives to direct laryngoscopy for intubation, but further large scale prospective studies comparing these devices to direct laryngoscopy in routine anesthesiology practice are needed. We hypothesized that the first pass success rate with […]

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Uncategorized Published - 9 June, 2015    By - Dr Clemens
Treatment with prolonged-release oxycodone/naloxone improves pain relief and opioid-induced constipation compared with prolonged-release oxycodone in patients with chronic severe pain and laxative-refractory constipation

Published in Clin Ther. 2015 April 1; 37(4) 784-92 Authors: Poelaert J et al PURPOSE: Laxative-refractory opioid-induced constipation (OIC) is defined as OIC despite using 2 laxatives with a different mechanism of action (based on the Anatomical Therapeutic Chemical Classification System level 4 term [contact laxatives, osmotically acting laxatives, softeners/emollients, enemas, and others]). OIC has […]

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Uncategorized Published - 9 June, 2015    By - Dr Clemens
Abuse-Deterrent OxyContin Won’t Solve US Opioid Epidemic

This is for our pain doctors. Abuse-deterrent formulations (ADFs) of opioid analgesics can have the intended purpose of curtailing abuse, but their effectiveness has “clear limits,” a new study confirms. Theodore J. Cicero, PhD, and Matthew S. Ellis, MPE, from Washington University, in St. Louis, Missouri, found that introduction of ADF oxycodone (OxyContin, Purdue Pharma […]

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Uncategorized Published - 9 June, 2015    By - Dr Clemens
DEA Issues Warning on Dangers of Fentanyl

The United States Drug Enforcement Administration (DEA) issued a nationwide alert to warn the public—and law enforcement in particular—about the dangers of fentanyl and its analogues/compounds. The DEA reported that heroin abuse and fentanyl-related seizures is on the rise. Fentanyl submissions increased from 942 to 3,344 between 2013 and 2014, according to data from the […]

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Uncategorized Published - 8 June, 2015    By - Dr Clemens
Effects of propofol or desflurane on post-operative spirometry in elderly after knee surgery: a double-blind randomised study

Published in Acta Anaesthesiol Scand. 2015 Jul;59(6):788-95. Authors: Kim YS  et al BACKGROUND: Intravenous or volatile agents reduce respiratory function, which can result in respiratory complications in geriatric patients. We hypothesised that there would be no differences in lung function between anaesthesia established using either drug. METHODS: Elderly patients were randomly assigned to receive either propofol […]

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Uncategorized Published - 8 June, 2015    By - Dr Clemens
FDA Launches Drug Shortages Mobile App

The FDA launched its first free mobile app specifically designed to speed public access to valuable information about drug shortages. The app identifies current drug shortages, resolved shortages and discontinuations of drug products. Drug shortages are a fact of life for hospital pharmacists, and can lead health care professionals to rely on alternative drug products, […]

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Uncategorized Published - 8 June, 2015    By - Dr Clemens
Postop Cognition in Elderly Improved With Dexamethasone

One of the main adverse events faced by elderly patients undergoing surgery is postoperative cognitive dysfunction (POCD). Yet, according to researchers at the University of Sao Paulo, in Brazil, the incidence of POCD appears to be manageable with the addition of dexamethasone to a general anesthetic regimen, especially one that uses light anesthesia. As reported […]

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Uncategorized Published - 8 June, 2015    By - Dr Clemens
Bedside Transtracheal Ultrasound Accurately Confirms Endotracheal Tube Placement

Authors: Das SK et al., Can J Anaesth 2015 Apr 62:413 In a meta-analysis, transtracheal ultrasound was highly sensitive and specific for detecting tracheal placement during emergency intubation. Transtracheal ultrasound verification of endotracheal intubation. Shows one air-mucosa interface with comet-tail artifact for tracheal intubation and two air-mucosa interfaces with comet-tail artifact or double-track sign for esophageal intubation. […]

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