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Authors: Oskar Kjærgaard Hørsdal, B.M.Sc. et al Anesthesiology December 2024, Vol. 141, 1105–1118. Background Cardiogenic shock (CS) presents a medical challenge with limited treatment options. Positive end-expiratory pressure (PEEP) during mechanical ventilation has been linked with clinical benefits in patients with CS. This study investigated whether increasing PEEP levels could unload the left ventricle (LV) in […]
Read MoreWe are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
Read MoreAuthors: Andrew G. Percy, M.D. et al Anesthesiology December 2024, Vol. 141, 1095–1104. Background Mechanical power is a summary variable quantifying the risk of ventilator-induced lung injury. The original mechanical power equation was developed using square flow ventilation. However, most children are ventilated using decelerating flow. It is unclear whether mechanical power differs according to mode […]
Read MoreAuthors: J. Robert Sneyd, M.D., Ph.D.; Brian J. Anderson, M.B., Ch.B., Ph.D. Anesthesiology December 2024, Vol. 141, 1034–1038. City dwellers of a certain age will recall lengthy waits for a bus followed eventually by the arrival of three on the same route driving nose-to-tail. So it is with intravenous hypnotics. Since the discovery of propofol, it has […]
Read MoreAuthor: Girish P. Joshi, M.B.B.S., M.D. Anesthesiology December 2024, Vol. 141, 1031–1033. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as valuable therapeutic options for managing type 2 diabetes mellitus because they allow glycemic control without increasing the potential for hypoglycemia. Also, they provide significant cardiovascular and renal benefits as well as lead to weight loss. In addition to […]
Read MoreFueling the heartbeat: Dynamic regulation of intracellular ATP during excitation-contraction coupling in ventricular myocytes. Proc Natl Acad Sci USA 2024; 121:e2318535121. PMID: 38865270. Author: Michael Zaugg, M.D., M.B.A. The human cardiac muscle requires a vast amount of adenosine triphosphate (ATP) for the approximately 100,000 beats/day. This study investigated the impact of excitation-contraction coupling on the […]
Read MoreAuthors: Jacob C. Jackson, M.D. et al Anesthesiology December 2024, Vol. 141, 1065–1074. Background The efficacy of serratus anterior plane block for treatment of pain after minimally invasive thoracic surgery remains unclear. This trial assesses the impact of serratus anterior plane block on postoperative opioid consumption and on measures of early recovery after thoracoscopic lung resection. […]
Read MoreAuthors: Rita Saynhalath, M.D. et al Anesthesiology December 2024, Vol. 141, 1075–1085. Background The Trial Remifentanil DEXmedetomidine (TREX) trial aimed to determine whether, in children less than 2 yr old, low-dose sevoflurane/dexmedetomidine/remifentanil anesthesia is superior to standard-dose sevoflurane anesthesia in terms of global cognitive function at 3 yr of age. The aim of the current secondary […]
Read MoreAuthors: Doug Campbell et al Anesthesiology December 2024, Vol. 141, 1086–1094. Background The Gompertz–Makeham law describes a characteristic pattern of mortality in human populations where the death rate is near constant between ages 18 and 30 yr (Makeham law) and rises exponentially thereafter (Gompertz law). This pattern has not been described in surgical populations, but if […]
Read MoreWe are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
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