J Pediatr 2015 May;166(5):1226-32 Authors: Belmont AP et al OBJECTIVE: To assess the rates and types of complications associated with deep sedation in children with sickle cell disease (SCD) and to explore potential risk factors. STUDY DESIGN: This was a retrospective cohort study of children with SCD and a comparison group of children without SCD who underwent […]
Read MoreMedicine (Baltimore) 2015 Apr;94(14):e597 Authors: Li B et al Abstract Many studies have reported the beneficial effects of dexmedetomidine on postoperative neurocognitive function but overall evidence is not as clear. We examined this conundrum by meta-analyzing studies that used dexmedetomidine in perioperative conditions or as intensive care unit (ICU) sedation and utilized reliable neurocognitive assessment tests. The […]
Read MoreThe US Food and Drug Administration has approved fentanyl iontophoretic transdermal system (Ionsys, The Medicines Co), the first needle-free, patient-controlled, preprogrammed fentanyl delivery system for management of acute postoperative pain in adults requiring opioid analgesia in the hospital, according to a company news release. Ionsys is a “novel alternative” to traditional intravenous patient-controlled analgesia that uses […]
Read MoreWorld J Gastroenterol 2015 Mar 28;21(12):3671-8. Authors: Kim N et al AIM: To compare the efficacy and safety of sedation protocols for endoscopic submucosal dissection (ESD) between dexmedetomidine-remifentanil and propofol-remifentanil. METHODS: Fifty-nine patients scheduled for ESD were randomly allocated into a dexmedetomidine-remifentanil (DR) group or a propofol-remifentanil (PR) group. To control patient anxiety, dexmedetomidine or propofol was […]
Read MoreActa Anaesthesiol Scand 2015 Apr 21 Authors: Heid F et al BACKGROUND: Pelvic intraoperative neuromonitoring (pIONM) aims to identify and spare the autonomic nerves and maintain patients’ quality of life. The effect of anaesthetic agents on the pIONM signal is unknown; therefore, the aim of the present study was to compare the influences of inhalation anaesthesia (IA) […]
Read MoreActa Anaesthesiol Scand 2015 Apr 21. Authors: Florkiewicz P et al BACKGROUND: Remifentanil, an ultra-short-acting opioid, provides intensive analgesia without prolonged respiratory depression and is widely used in cardiac surgery. Diminished dosing may also offer stable hemodynamics, even during sternotomy and sternal retraction. However, increased postoperative pain and induced opioid tolerance after remifentanil dosing during abdominal surgery […]
Read MoreAnesthesia & Analgesia: July 2015- Volume 121-Issue 1- p 219-222 Authors: Fahy, Brenda G. MD et al Obtaining anesthesia informed consent for a series of repetitive debridements in burn-injured patients requires a significant time investment for anesthesiologists and patient families. A single consent form was introduced that covered multiple related anesthetics in burn patients. The […]
Read MoreAnesthesia & Analgesia: April 28, 2018 Authors: Dexter, Franklin MD, PhD et al BACKGROUND: We analyze data from the American Society of Anesthesiologist’s (ASA) Anesthesia Quality Institute (AQI) to report the U.S. anesthesia workload by time of day and day of the week. We consider the extent to which first case starts, rather than durations […]
Read MoreThe transition from extensive use of intravenous (IV) sedation for interventional pain procedures to almost exclusive use of oral anxiolysis at an outpatient pain center led to significant improvements in patient satisfaction and recovery times, a new study shows. But not all practitioners are on board with such a policy, citing potential safety issues. “The […]
Read MoreMore than half of Medicare beneficiaries undergoing cataract surgery undergo at least one preoperative test, despite strong evidence showing that preoperative tests are not associated with any improvement in outcomes, new research shows. Moreover, the prevalence of preoperative testing before cataract surgery is not different than it was 20 years ago, before the introduction of […]
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