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Anesthesia & Analgesia: June 2015 Volume 120 Issue 6 p1273-1285 Authors: Correa, Denis MBBS, MD et al BACKGROUND: Chronic opioid use has been associated with the development of sleep-disordered breathing (SDB) such as central sleep apnea (CSA). Patients receiving chronic opioids may suffer from unrecognized sleep apnea that contributes to opioid-overdose death. Currently, information regarding […]
Read MoreAnesthesia & Analgesia: June 2015 Volume 120 Issue 6 o 1214-1224 Postoperative Sleep-Disordered Breathing in Patients Without Preoperative Sleep Apnea Authors: Chung, Frances MBBS, FRCPC et al BACKGROUND: Recently published data show that postoperative apnea-hypopnea index (AHI) is significantly increased in some patients without preoperative sleep apnea. These patients may be at risk of developing […]
Read MorePublished in JAMA Facial Plast Surg, 2015 Jul 1;17(4):251-5. Authors: Trimas SJ et al IMPORTANCE: Patients who experience immediate postoperative nausea and vomiting (PONV) after their facial plastic surgery procedure have a higher incidence of complications and dissatisfaction. OBJECTIVES: To determine whether a single dose of aprepitant administered preoperatively can decrease the incidence of immediate PONV in […]
Read MorePublished in BMJ, 2015 May 14;350:h2102. Authors: Desai RJ et al OBJECTIVE: To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk factors of history of opioid misuse or dependence, misuse of other substances, non-opioid […]
Read MoreThe walls have ears, as the saying goes, but so do sedated patients whose smartphones have been set to “record.” In a recently concluded malpractice trial, that fact not only cost a Maryland doctor some money but subsequently her job, as a June 23 story in the Washington Post reports. The case involved a Vienna, Virginia, man […]
Read MorePublished in J Clin Anesth. 2015 May 30. pii: S0952-8180(15)00148-8 Authors: Linganna RE et al STUDY OBJECTIVE AND DESIGN: The mechanism of action of commonly used general anesthetics is largely unknown. One hypothesized mechanism is through modulation of microtubule stability. Taxanes, a subset of chemotherapeutic drugs known to alter microtubule stability and commonly used to treat breast […]
Read MorePublished in Drugs Aging. 2015 Jun;32(6):419-26. Authors: Veal FC et al Abstract Persistent pain affects the elderly disproportionally, occurring in 50 % of elderly community-dwelling patients and 80 % of aged care residents. The management of pain in the elderly and frail patient is complicated because of the risks posed by changes in pharmacokinetics and pharmacodynamics, polypharmacy, and drug-disease […]
Read MoreLiposomal-encased bupivacaine (LEB) is a good, cost-effective medical choice for pain control after breast surgery. Valerie Lemaine, MD, MPH, an assistant professor of plastic surgery and the vice chair for research at Mayo Clinic College of Medicine, Rochester, Minn., reviewed her experience at the 32nd Annual Miami Breast Cancer Conference. She noted that the drug […]
Read MoreDespite obvious challenges in identifying appropriate candidates, mechanically ventilated patients can safely self-administer sedative medications using widely available infusion pumps, a research team has concluded. Although the researchers’ primary focus was not the efficacy of the patient-controlled sedation (PCS) system, they hope to delve deeper into outcomes in future studies. “For many years, the paradigm […]
Read MoreM-Irfan Suleman, MD All research for this report was undertaken while the author was: Assistant Professor of Anesthesiology Director of Pediatric Regional Anesthesia Department of Anesthesiology Arkansas Children’s Hospital and University of Arkansas for Medical Sciences Little Rock, Arkansas I describe here a new, modified, ultrasound-guided penile block for male pediatric patients undergoing circumcision. The […]
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