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Pharmacotherapy. 2015 May;35(5):477-81 Authors: White S et al STUDY OBJECTIVE: To determine whether liposomal bupivacaine, a long-acting anesthetic indicated for single-dose wound infiltration to produce postoperative analgesia, has an impact on postoperative pain in patients undergoing total knee arthroplasties (TKAs). DESIGN: Single-center retrospective cohort study. SETTING: Large tertiary and quaternary care hospital. PATIENTS: A total of 120 […]
Read MoreAlthough many anesthesiologists do not routinely reverse neuromuscular blockade at the end of surgery, a study has found that patients who are left to spontaneously recover from such blockade are six times as likely to need reintubation within 48 hours of surgery as their counterparts who received a reversal agent. Of the modifiable risk factors […]
Read MoreWeight reduction, improving leg strength, and taking a global approach to the treatment of pain in general may reduce the prevalence and incidence of foot pain in older, community-dwelling adults, according to results of a large, longitudinal observation study presented at the 2015 Osteoarthritis Research Society International (OARSI) World Congress. “Weight, poorer leg strength, and […]
Read MoreThe use of cryotherapy after normal vaginal delivery has no effect on perineal pain or oedema, according to a study presented here at the 63rd Annual Meeting of the American College of Obstetricians and Gynecologists (ACOG). “It’s a little disappointing because we expected that the cryotherapy really could relieve pain and oedema, but it was […]
Read MoreActa Anaesthesiol Scand. 2015 May 1 Authors: Eskildsen KZ et al BACKGROUND: Early postoperative mobilisation may reduce patient morbidity and improve hospital efficiency by accelerated discharge. The aim of this study was to measure postural stability early after laparoscopic surgery in order to assess how early it is safe to mobilise and discharge patients. METHODS: We included […]
Read MoreDespite the apparent risks, using a neuromuscular blocking agent (NMBA) before tracheal intubation improves the odds of first-attempt intubation success in critically ill ICU patients, a study has found. “The question of whether to paralyze or not to paralyze is clearly answered in the operating room and emergency department: Using a paralytic is the way […]
Read MoreChildren routinely face prolonged periods without eating or drinking before surgery, often extending hours beyond recommended guidelines, a new study has found. More than three-fourths of children who had surgery went more than 12 hours without solids before their operations, researchers at Boston Children’s Hospital reported. The study, which examined the records of more than […]
Read MoreActa Anaesthesiol Scand. 2015 May 5. doi: 10.1111/aas.12521. Authors: Kurita GP et al BACKGROUND: Renal impairment and the risk of toxicity caused by accumulation of opioids and/or active metabolites is an under-investigated issue. This study aimed at analysing if symptoms/adverse effects in opioid-treated patients with cancer were associated with renal function. METHODS: Cross-sectional multicentre study (European Pharmacogenetic […]
Read MoreActa Anaesthesiol Scand. 2015 April;59(7):921-7 Authors: Marashi SM et al BACKGROUND: In this study, the effect of naloxone on duration of supraclavicular brachial plexus block was evaluated. It was hypothesized that naloxone can increase the duration of neural blockade. METHODS: Sixty-eight patients scheduled for surgery under supraclavicular brachial plexus block were randomly assigned to receive 30 ml bupivacaine […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1405-1412 Authors: Hausman, Mark S. Jr. MD et BACKGROUND: Surgical patients with chronic obstructive pulmonary disease (COPD) are at increased risk of perioperative complications. In this study, we sought to quantify the benefit of avoiding general anesthesia in this patient population. METHODS: Data from the […]
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