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Anesthesiology 8 2015, Vol.123, 444-456 Authors: Anthony T. Machi MD et al Background: The authors conducted a randomized, controlled, parallel-arm, superiority study to test the hypothesis that a continuous adductor canal block decreases the time to attain four discharge criteria compared with a continuous femoral nerve block after tricompartment knee arthroplasty. Methods: Subjects undergoing tricompartment knee arthroplasty were randomized […]
Read MoreAnesthesiology 8 2015, Vol.123, 434-443 Authors: Maurice Jove, MD et al Background: Complications with IV patient-controlled analgesia include programming errors, invasive access, and impairment of mobility. This study evaluated an investigational sufentanil sublingual tablet system (SSTS) for the management of pain after knee or hip arthroplasty. Methods: This prospective, randomized, parallel-arm, double-blind study randomized postoperative patients at 34 U.S. sites […]
Read MoreAnesthesiology 8 2015, Vol.123, 320-326. Authors: David T. Monks, MD et al Background: Studies examining the efficacy of a single preoperative dose of gabapentin for analgesia after cesarean delivery (CD) have been inconclusive. The authors hypothesized that a perioperative course of gabapentin would improve analgesia after CD. Methods: This single-center, randomized, double-blind, placebo-controlled, parallel-group, superiority trial was […]
Read MoreAnesthesiology 8 2015, Vol.123, 288-306. Authors: Susan M Lee, MD, FRCPC et al Background: Despite widespread use, there is limited information to guide perioperative management of angiotensin receptor blockers (ARBs). Methods: In this retrospective cohort study, the authors evaluated the patterns of postoperative ARB use in veterans regularly prescribed ARBs admitted for noncardiac surgery at the Veterans […]
Read MoreAnesthesiology 8 2015, Vol.123, 272-287. Authors: Andra E Duncan, MD et al Background: Glucose–insulin–potassium (GIK) administration during cardiac surgery inconsistently improves myocardial function, perhaps because hyperglycemia negates the beneficial effects of GIK. The hyperinsulinemic normoglycemic clamp (HNC) technique may better enhance the myocardial benefits of GIK. The authors extended previous GIK investigations by (1) targeting normoglycemia while […]
Read MoreAuthors: Mort TC and Braffett BH., Anesth Analg 2015 Jun 23; Video laryngoscopy improved first-attempt success and lowered rates of complications compared with direct laryngoscopy in a single-center registry study of endotracheal tube exchanges using airway exchange catheters. Endotracheal tube (ETT) exchange is required when ventilation is ineffective because of either cuff failure or tube size. The […]
Read MoreWeight loss in patients with types 1 and 2 diabetes is linked with an improvement in diabetic neuropathy, independent of blood glucose levels, according to results of a parallel-group study reported at the 75th Scientific Sessions of the American Diabetes Association meeting. “To our knowledge, weight loss has not been shown previously to improve diabetic […]
Read MoreEur J Pain, 2015 May 29. Authors: Orbach-Zinger et al BACKGROUND: Quantitative sensory testing (QST) measures response to painful stimuli and has been used to predict post-caesarean pain. Pain reported upon intravenous cannulation was shown to predict epidural analgesic use and pain intensity during labour. We hypothesized that pain intensity reported by women upon local anaesthesia injection […]
Read MoreThe US Food and Drug Administration (FDA) has approved the Senza spinal cord stimulation (SCS) system (Senza System, Nevro) to aid in the management of chronic intractable pain of the trunk and/or limbs, including pain associated with failed back surgery syndrome, low back pain, and leg pain. The new system is able to reduce pain […]
Read MoreBMC Anesthesiol. 2015;15(21) Authors: Wonjung Hwang et al Background Total intravenous anesthesia (TIVA) is used widely in spinal surgery because inhalational anesthetics are known to decrease the amplitude of motor evoked potentials. Presently, dexmedetomidine is used as an adjuvant for propofol-based TIVA. We compared the effects of remifentanil and dexmedetomidine on pain intensity as well as the […]
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