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Uncategorized Published - 8 September, 2015    By - Dr Clemens
Benadryl as an Adjuvant in Migraine Treatment?

This is for our providers who treat pain patients. Authors: Friedman BW et al., Ann Emerg Med 2015 Aug 27; Adding a large dose of diphenhydramine to metoclopramide therapy did not improve outcomes. Acute migraine is best treated with sumatriptan, prochlorperazine, caffeine, ibuprofen, or a combination, and opioids should be avoided assiduously. Metoclopramide is often used instead […]

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Uncategorized Published - 4 September, 2015    By - Dr Clemens
Spinal anaesthesia with adjunctive intrathecal morphine versus continuous lumbar plexus blockade: a randomised comparison for analgesia after hip replacement

Anaesth Intensive Care 2015 Jul;43(4):449-53. Authors: Fredrickson MJ et al Abstract Following elective total hip replacement, both continuous lumbar plexus blockade and spinal anaesthesia (with adjunctive intrathecal morphine) have shown early outcome benefits over opioid analgesia and single-injection nerve block. However, the two techniques have not been compared in a prospective randomised manner. Our study examined 50 […]

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Uncategorized Published - 4 September, 2015    By - Dr Clemens
Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death

Authors: Mark D Willingham MD, M.C.S.I. et al Anesthesiology Published on 8 2015 Background: An intraoperative concurrence of mean arterial pressure less than 75 mmHg, minimum alveolar concentration less than 0.8, and bispectral index less than 45 has been termed a “triple low” state. An association between triple low and postoperative mortality has been reported but was not […]

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Uncategorized Published - 4 September, 2015    By - Dr Clemens
Music Appears to Reduce Postoperative Pain, Anxiety

Patients who listen to music around the time of surgery — even while under general anesthesia — reap substantial postoperative benefits, a Lancet systematic review finds. The analysis included over 70 randomized trials in which music before, during, or after surgery was compared with usual care or non-pharmacologic interventions (e.g., white noise, bed rest). Roughly […]

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Uncategorized Published - 4 September, 2015    By - Dr Clemens
Addition of Dexamethasone and Buprenorphine to Bupivacaine Sciatic Nerve Block: A Randomized Controlled Trial

Regional Anesthesia & Pain Medicine: July/August 2015-Volume 40-Issue 4-p 321-329 Authors: YaDeau, Jacques T. MD, PhD et al Background and Objectives: Sciatic nerve block provides analgesia after foot and ankle surgery, but block duration may be insufficient. We hypothesized that perineural dexamethasone and buprenorphine would reduce pain scores at 24 hours. Methods: Ninety patients received […]

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Uncategorized Published - 4 September, 2015    By - Dr Clemens
Low Cerebral Oxygenation Levels during Resuscitation in Out-of-hospital Cardiac Arrest Are Associated with Hyperfibrinolysis

Authors: Anne Duvekot, MD et al Anesthesiology Published on 8 2015 Background: The authors investigated whether patients with out-of-hospital cardiac arrest with an initial low cerebral oxygen level during cardiopulmonary resuscitation are more prone to develop hyperfibrinolysis than patients with normal cerebral oxygenation levels and which part of the fibrinolytic system is involved in this response. Methods: In 46 […]

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Uncategorized Published - 3 September, 2015    By - Dr Clemens
A randomised controlled trial comparing three analgesia regimens following total knee joint replacement: continuous femoral nerve block, intrathecal morphine or both

Anaesth Intensive Care. 2015 Jul;43(4):454-60 Authors: Olive DJ et al Abstract This randomised controlled trial compared three analgesia regimens following primary unilateral total knee joint replacement: continuous femoral nerve block (CFNB), intrathecal morphine (ITM), and both. The primary outcome was pain ratings over the first 24 hours. Secondary outcomes included morphine consumption, nausea, pruritus and […]

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Uncategorized Published - 3 September, 2015    By - Dr Clemens
Comparison of ultrasound-guided supraclavicular, infraclavicular and below-C6 interscalene brachial plexus block for upper limb surgery: a randomised, observer-blinded study

Anaesth Intensive Care. 2015 Jul;43(4):468-72. Authors: Bharti N et al Abstract This prospective, randomised, observer-blinded study was conducted to compare the ease of performance and surgical effectiveness of interscalene block below the C6 nerve root with supraclavicular and infraclavicular techniques of brachial plexus block for upper arm and forearm surgery. Sixty adult patients of American […]

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Uncategorized Published - 3 September, 2015    By - Dr Clemens
Continuous Adductor Canal Versus Continuous Femoral Nerve Blocks: Relative Effects on Discharge Readiness Following Unicompartment Knee Arthroplasty

Reg Anesth Pain Med. 2015 Sep-Oct;40(5):559-67 Authors: Sztain JF et al BACKGROUND: We tested the hypothesis that, following unicompartment knee arthroplasty, a continuous adductor canal block decreases the time to reach 4 discharge criteria compared with a continuous femoral nerve block. METHODS: Subjects were randomized to either an adductor canal or femoral perineural catheter (2-day […]

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Uncategorized Published - 3 September, 2015    By - Dr Clemens
Ondansetron Does Not Attenuate Hemodynamic Changes in Patients Undergoing Elective Cesarean Delivery Using Subarachnoid Anesthesia: A Double-Blind, Placebo-Controlled, Randomized Trial

Reg Anesth Pain Med. 2015 Jul-Aug;40(4):344-8 Authors: Terkawi AS et al INTRODUCTION: Hypotension is the most common complication after subarachnoid anesthesia for cesarean delivery. Several therapeutic and preventive measures are used to attenuate this side effect. Serotonin receptor-blocking drugs have been suggested as one such approach. We sought to determine whether prophylactically administered intravenous ondansetron […]

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