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Uncategorized Published - 1 October, 2015    By - Dr Clemens
Quadratus lumborum block for postoperative pain after caesarean section: A randomised controlled trial

Eur J Anaesthesiol 2015 Jul 29 Authors: Blanco R et al BACKGROUND: Effective postoperative analgesia after caesarean section is important because it enables early ambulation and facilitates breast-feeding. Several case reports have shown that local anaesthetic injection around the quadratus lumborum muscle is effective in providing pain relief after various abdominal operations and in patients with chronic […]

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Uncategorized Published - 1 October, 2015    By - Dr Clemens
Influence of Dexmedetomidine on the Tourniquet Related Responses in Hypertension Patients Receiving Unilateral Knee Arthroplasty under General Anesthesia

J Arthroplasty 2015 Aug;30(8):1359-63 Authors: Li YH et al Abstract This study aimed to investigate the influence of dexmedetomidine (DEX) on the tourniquet related responses in hypertension patients receiving unilateral knee arthroplasty (UKA) under general anesthesia. Results showed that the incidence of tourniquet induced hypertension (TIH), hemodynamics, MAC and EtSEV in DEX group were significantly lower than […]

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Uncategorized Published - 30 September, 2015    By - Dr Clemens
Preoperative Slow-Release Morphine Reduces Need of Postoperative Analgesics and Shortens Hospital Stay in Laparoscopic Gastric Bypass

Obes Surg 2015 Jul Authors: Hedberg J et al BACKGROUND: As most bariatric procedures are performed by laparoscopy, hospital stay is exceptionally short, despite the habitus of patients and the rather extensive intra-abdominal surgery. To facilitate postoperative mobilization, most patients are given repeated single doses of morphine, a drug with several side effects. We aimed to evaluate […]

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Uncategorized Published - 30 September, 2015    By - Dr Clemens
The Use of Lidocaine Containing Cardioplegia in Surgery for Adult Acquired Heart Disease

J Card Surg 2015 Sep;30(9):677-84 Authors: Yammine M et al BACKGROUND: Del Nido cardioplegia, a crystalloid-based solution with lidocaine as a key element, is given as a single dose and has been used successfully in congenital cardiac surgery. HYPOTHESIS: We retrospectively compared a lidocaine containing “modified del Nido” solution with our standard whole blood cardioplegia to investigate […]

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Uncategorized Published - 30 September, 2015    By - Dr Clemens
Safety and Side Effect Profile of Liposome Bupivacaine (Exparel) in Peripheral Nerve Blocks

Reg Anesth Pain Med 2015 Sep-Oct;40(5):572-82 Authors: Ilfeld BM et al BACKGROUND: Liposome bupivacaine (Exparel) is a multivesicular liposomal formulation of bupivacaine currently approved in the United States for single-dose administration into the surgical site to provide postsurgical analgesia. This retrospective analysis examined safety data from clinical trials involving the off-label use of this formulation in peripheral […]

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Uncategorized Published - 30 September, 2015    By - Dr Clemens
Comparison of different anesthesia techniques during esophagogastroduedenoscopy in children: a randomized trial

Paediatr Anaesth 2015 Oct;25(10):1013-9 Authors: Patino M et al BACKGROUND: Esophagogastroduedenoscopy (EGD) in children is usually performed under general anesthesia. Anesthetic goals include minimization of airway complications while maximizing operating room (OR) efficiency. Currently, there is no consensus on which anesthetic technique best meets these goals. We performed a prospective randomized study comparing three different anesthetic techniques. […]

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Uncategorized Published - 30 September, 2015    By - Dr Clemens
Cardiac Dysrhythmias in Children Undergoing Extracorporeal Shock Wave Lithotripsy Under General Anesthesia or Propofol Sedation: A Prospective, Observational Cohort Study

Urology 2015 Jul AUTHORS: Mathers J et al OBJECTIVE: To assess the frequency and severity of cardiac dysrhythmias and identify any intraoperative or postoperative complications in children undergoing extracorporeal shock wave lithotripsy (ESWL). METHODS: All children coming to our institution for ESWL from June 2014 to January 2015 were prospectively enrolled in an observational cohort study. Intraoperative […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Intranasal midazolam during presurgical epilepsy monitoring is well tolerated, delays seizure recurrence, and protects from generalized tonic-clonic seizures

Epilepsia. 2015 Sep;56(9):1408-14 AUTHORS: Kay L et al OBJECTIVE: To evaluate the tolerability and efficacy of the ictal and immediate postictal application of intranasal midazolam (in-MDZ) in adolescents and adults during video-electroencephalography (EEG) monitoring. METHODS: Medical records of all patients treated with in-MDZ between 2008 and 2014 were reviewed retrospectively. For each single patient, the time […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Urethrocutaneous fistula following hypospadias repair: regional anesthesia and other factors

Paediatr Anaesth. 2015 Jul AUTHORS; Zaidi RH et al BACKGROUND: Urethrocutaneous fistula is a well-known complication of hypospadias surgery. A recent prospective study by Kundra et al. (Pediatr Anesth 2012) has suggested that caudal anesthesia may increase the risk of fistula formation. We sought to evaluate this possible association and determine if any other novel factors may […]

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Uncategorized Published - 29 September, 2015    By - Dr Clemens
Propofol Regulates the Surface Expression of GABAA Receptors: Implications in Synaptic Inhibition

Anesthesia & Analgesia: August 2015 AUTHORS: Li, Yuwen PhD et al BACKGROUND: The anesthetic propofol is thought to induce rapid hypnotic sedation by potentiating [gamma]-aminobutyric acid receptor (GABAAR) activity. Little is known about the molecular mechanisms of propofol in modulating inhibitory synaptic transmission. We aimed to investigate the role of propofol in modulating surface expression […]

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