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The Centers for Disease Control and Prevention (CDC) has issued an alert about increases in fentanyl drug confiscations and fentanyl-related overdose fatalities. Reports from the National Forensic Laboratory Information System, a program of the Drug Enforcement Administration’s (DEA’s) Office of Diversion Control, indicate a significant increase in the total number of fentanyl drug seizures reported […]
Read MoreCNS Drugs, 2015 Jul;29(7):543-63. doi: 10.1007/s40263-015-0259-6. Authors: Chidambaran V et al Abstract Propofol is an intravenous agent used commonly for the induction and maintenance of anesthesia, procedural, and critical care sedation in children. The mechanisms of action on the central nervous system involve interactions at various neurotransmitter receptors, especially the gamma-aminobutyric acid A receptor. Approved for use […]
Read MoreCan J Anaesth 2015 Oct;62(10):1045-1054. Authors: Tabing AK et al et al PURPOSE: Cost effectiveness is becoming increasingly important in today’s healthcare environment. Remifentanil, dexmedetomidine, and desflurane are costly agents that often have suitable alternatives to their use. We sought to identify changes in cost and outcomes following interventions that limited the availability of these drugs. […]
Read MoreFaculty Reviewers Carlos Artime, MD Assistant Professor Department of Anesthesiology The University of Texas Health Science Center at Houston Houston, Texas Kenneth Candido, MD Chairman Department of Anesthesiology Advocate Illinois Masonic Medical Center Chicago, Illinois Julie Golembiewski, PharmD Clinical Associate Professor Clinical Pharmacist University of Illinois College of Medicine at Chicago Chicago, Illinois Tricia Meyer, […]
Read MorePain Aug 2015 Authors: Nielsen RV et al Glucocorticoids have attracted increasing attention as adjuvants in the treatment of acute postoperative pain. Further, anecdotal reports may support glucocorticoids for preventing sustained postoperative pain. We explored preoperative dexamethasone combined with paracetamol and ibuprofen on acute and sustained pain after lumbar disc surgery. In this blinded study […]
Read MoreA year after having an MI, patients who still smoked were more likely to have angina, and they scored worse on mental- and physical-health aspects of quality of life, compared with other patients, in a new study. However, patients who had quit smoking before their MI had a similar health status as patients who never […]
Read MoreAlthough there is widespread agreement that showering with chlorhexidine gluconate reduces skin bacteria before surgery, there are no definitive data that this practice is effective in reducing postoperative surgical site infections (SSIs). New data, published August 26 in JAMA Surgery, may settle that question. Charles E. Edmiston Jr, PhD, from the Division of Vascular Surgery, Department […]
Read MoreWhether a surgeon works the night before performing surgery does not change the risk for adverse outcomes, a new study shows. “These data suggest that calls for broad-based policy shifts in duty hours and practices of attending surgeons may not be necessary at this time,” write Anand Govindarajan, MD, from the Institute for Clinical Evaluative […]
Read MoreAuthors: Jean Guglielminotti, M.D., Ph.D. et al Anesthesiology 9 2015 Background: Cesarean delivery (CD) is associated with significantly increased risks of anesthesia-related adverse events (ARAEs) and nonanesthetic perioperative morbidity compared with vaginal delivery. Temporal trends in these adverse outcomes remain unknown despite efforts to improve maternal safety. This study examines temporal trends in ARAEs and nonanesthetic perioperative […]
Read MoreAnesthesia & Analgesia: Post Author Corrections: August 25, 2015 AUTHORS: Babazade, Rovnat MD et al BACKGROUND: Sjogren syndrome is a chronic autoimmune disorder of the exocrine glands associated with cardiovascular events. We aimed to evaluate postoperative complications in patients with Sjogren syndrome undergoing noncardiac surgery. Specifically, we tested the primary hypothesis that patients with Sjogren […]
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