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Authors: Shiyang Li et al BMC Anesthesiol. 2016;16(24) Background: Propofol and fentanyl are the most widely administered anesthesia maintaining drugs during colonoscopy. In this study, we determined the median effective concentration (EC50) of propofol required for colonoscopy in elderly patients, and the purpose of this study was to describe the pharmacodynamic interaction between fentanyl and propofol when […]
Read MoreCommon surgical procedures were associated with increased risk for chronic opioid use in the first year after surgery by opioid-naïve patients and some patients were particularly vulnerable, according to a study published online by JAMA Internal Medicine. Opioid sales have increased dramatically over the last decade, especially to relieve noncancer pain, resulting in increased opioid-related […]
Read MoreWomen who undergo axillillary node surgery for breast cancer are much more likely to develop chronic pain, according to a study published in the Canadian Medical Association Journal (CMAJ). “Ten-year survival rates for breast cancer patients are now around 83%, but up to 60% of women who undergo surgery as part of cancer treatment, may develop […]
Read MoreResearchers have uncovered a more effective way of treating fibromyalgia by combining with duloxetine. The combination can safely improve outcomes in patients with fibromyalgia, including relief from pain, physical function, and overall quality of life. “Previous evidence supports added benefits with some drug combinations in fibromyalgia,” said Ian Gilron, MD, Queen’s University, Kingston, Ontario. “We […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 488–492 AUTHORS: Ghisi, Daniela MD et al BACKGROUND: In this randomized, controlled, observer-blinded study, we evaluated analgesia provided by transversus abdominis plane (TAP) block after elective total laparoscopic hysterectomy in terms of reduced postoperative morphine consumption as the primary end point. METHODS: […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 436–444 AUTHORS: Kim, Jeongmin MD, PhD et al BACKGROUND: In this study, we examined the relationship between postoperative cognitive dysfunction (POCD) and intraoperative regional cerebral oxygen saturation (rSO2) in elderly patients undergoing spinal surgery. METHODS: We enrolled 87 patients older than 65 […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 430–435 AUTHORS: Brown, Charles H. IV MD, MHS et al Delirium is common after cardiac surgery, and preoperative identification of high-risk patients could guide prevention strategies. We prospectively measured frailty in 55 patients before cardiac surgery and assessed postoperative delirium using a […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 420–429 AUTHORS: Willems, Ariane MD, MSci Biomed, PhD et al BACKGROUND: Children undergoing cardiac surgery are frequently exposed to red blood cell (RBC) transfusions mainly in the case of hemorrhage or low oxygen transport. However, in this population, RBCs are sometimes added […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 411–417 AUTHORS: Lin, Elaina E. MD et The anesthetic management for open fetal surgery has been described, but many therapeutic tenets have not been supported with data. We present data on the anesthetic management and outcomes of 65 patients undergoing ex utero […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 299–308 AUTHORS: Liou, Jing-Yang MD et al BACKGROUND: Selecting an effective dose of sedative drugs in combined upper and lower gastrointestinal endoscopy is complicated by varying degrees of pain stimulation. We tested the ability of 5 response surface models to predict depth […]
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