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Sufentanil sublingual tablets effectively control acute pain after outpatient abdominal surgery. Results from a multicenter, randomized, placebo-controlled study suggest that 30-mg tablets are “efficacious and well tolerated across a variety of ambulatory surgery procedures for the management of moderate to severe acute postoperative pain,” said Pamela Palmer, MD, PhD, chief medical officer and co-founder of […]
Read MoreRoughly 40% of women receiving intrathecal opioids for cesarean delivery experience hypercapnia, according to a study presented at the 2016 annual meeting of the Society for Obstetric Anesthesia and Perinatology. The researchers said the condition is underdetected in the obstetric population, as per the current guidelines of the American Society of Anesthesiologists (ASA). “Women with […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1567–1573 AUTHORS: Dexter, Franklin MD, PhD et al BACKGROUND: Anesthesiologists providing care during off hours (ie, weekends or holidays, or cases started during the evening or late afternoon) are more likely to care for patients at greater risk of sustaining major adverse […]
Read MoreAnesthesia & Analgesia: September 2016 AUTHORS: Choi, Eun Kyung MD, PhD et al BACKGROUND: Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrinato iron (III) (FeTMPyP) by selective […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1471–1479 AUTHORS: Belcher, Allan W. DO et al BACKGROUND: Opioids can contribute to postoperative desaturation. Short-acting opioids, titrated to need, may cause less desaturation than longer-acting opioids. We thus tested the primary hypothesis that long-acting patient-controlled intravenous opioids are associated with more […]
Read MoreAuthors: Vincent J. Alentado, BS et al Spine. 2016;41(14):1167-1172. Study Design. Retrospective Review. Objective. The aim of this study was to determine medical, radiographic, and surgical risk factors for the development of adjacent segment disease (ASD) after lumbar fusion. Summary of Background Data. ASD is a recognized outcome of spinal fusion that leads to increased costs and debilitating symptoms […]
Read MoreAnesthesia & Analgesia: November 2016 – Volume 123 – Issue 5 – p 1297–1301 AUTHORS: Dexter, Franklin MD, PhD et al BACKGROUND: In order to provide guidance to organizations considering elective weekend surgical case scheduling, we analyzed data from the American Society of Anesthesiologist’s Anesthesia Quality Institute. We determined the US anesthesia workload on Saturdays […]
Read MoreAuthors: Abdul Basit et al BMJ Open Diabetes Res Care. 2016;4(1) Objective: To assess the effect of high-dose vitamin D in patients with painful diabetic neuropathy. Methods: A single intramuscular dose of 600 000 IU vitamin D was administered, and the effects on metabolic parameters and neuropathic pain assessed over 20 weeks. Results: 143 participants with predominantly type 2 diabetes, […]
Read MorePlain x-rays are the best first-line screening tools for knee pain among middle-aged patients, according to a study published in the September issue of the Journal of American Academy of Orthopaedic Surgeons (JAAOS). Whether a patient will need surgery for knee problems depends on how much arthritis he or she has. “If an x-ray shows […]
Read MoreAuthors: Karthikesalingam A et al., N Engl J Med 2016 Nov 24; 375:2051 Mean abdominal aortic aneurysm diameter at the time of repair was significantly smaller in the U.S. International guidelines recommend that abdominal aortic aneurysm (AAA) repair be considered for AAAs with diameters ≥5.5 cm in men or ≥5.0 cm in women (Eur J Vasc Endovasc […]
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