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By Daniel M. Lindberg, MD Dr. Lindberg is an associate editor with NEJM Journal Watch Emergency Medicine, from which this story was adapted. Evidence that sweet solutions improve pain for neonates during painful procedures has been compelling for more than a decade, according to a meta-analysis in Pediatrics. Using a robust search strategy, researchers identified 168 randomized, […]
Read MoreEdited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Regular, long-term use of acetaminophen and nonsteroidal anti-inflammatory drugs is associated with modestly elevated risk for hearing loss in women, suggests an American Journal of Epidemiology study. Over 55,000 women aged 44–69 in the Nurses’ Health Study answered questions about incident hearing loss and how often they […]
Read MoreAuthors: Alejandra MD, PhD et al Objective: We report the results of a pilot, enrichment-design, placebo-controlled crossover trial of pregabalin for the treatment of prediabetic small-fiber neuropathic pain. Methods: Individuals with impaired fasting glucose or impaired glucose tolerance and neuropathic pain were evaluated according to UTAH Early Neuropathy Scale (UENS), Quantitative Sensory Testing, and intraepidermal […]
Read MoreWith mainstream attention focused on the opioid overdose epidemic in the US, prices for naloxone are rising substantially, leading doctors to call for legislative support to stop unjustified naloxone price increases. By Thomas G. Ciccone Interview with Ravi Gupta, BS, and commentary from Jeffrey Gudin, MD, and Jeff Fudin, PharmD As opioid overdose deaths continue to […]
Read MoreAuthors: Pavel S. Roshanov, M.D., M.Sc. et al Anesthesiology 1 2017, Vol.126, 16-27. Background: The effect on cardiovascular outcomes of withholding angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac surgery is unknown. Methods: In this international prospective cohort study, the authors analyzed data from 14,687 patients (including 4,802 angiotensin-converting enzyme inhibitor/angiotensin II […]
Read MoreAuthors: Paul A. Stricker, M.D. et al Anesthesiology published on December 15, 2016 Background: The Pediatric Craniofacial Collaborative Group established the Pediatric Craniofacial Surgery Perioperative Registry to elucidate practices and outcomes in children with craniosynostosis undergoing complex cranial vault reconstruction and inform quality improvement efforts. The aim of this study is to determine perioperative management, outcomes, […]
Read MoreThere will be no posts today in honor of Christmas.
Read MoreI want to wish all of our followers a Merry Christmas and Happy New Year!
Read MoreAuthors: Andrew J. Toner, F.R.C.A. et al Anesthesiology published on December 8, 2016. Background: Glucocorticoids are increasingly used perioperatively, principally to prevent nausea and vomiting. Safety concerns focus on the potential for hyperglycemia and increased infection. The authors hypothesized that glucocorticoids predispose to such adverse outcomes in a dose-dependent fashion after elective noncardiac surgery. Methods: The authors […]
Read MoreAuthors: Lukas Lannemyr, M.D. et al Anesthesiology published on December 8, 2016. Background: Acute kidney injury is a common complication after cardiac surgery with cardiopulmonary bypass. The authors evaluated the effects of normothermic cardiopulmonary bypass on renal blood flow, glomerular filtration rate, renal oxygen consumption, and renal oxygen supply/demand relationship, i.e., renal oxygenation (primary outcome) in […]
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