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Authors: Maher, Dermot P MD, MS et al Anesthesia & Analgesia: February 2017 – Volume 124 – Issue 2 – p 661–674 Chronic Pain Medicine: Narative Review Article Intravenous ketamine infusions have been used extensively to treat often-intractable neuropathic pain conditions. Because there are many widely divergent ketamine infusion protocols described in the literature, the variation […]
Read MoreWritten by DR. LEONARD A. SOWAH Current reports from the International Narcotics Control Board (INCB) suggest that the United States is second on the list of countries with the highest per capita consumption of opiates. Data from 2014 quotes U.S. use of opiates at 700 mg per capita per year. The only country that has […]
Read MoreMinimally invasive techniques for pancreatic surgery are associated with a significantly increased risk for complications when performed in low-volume hospitals in which relatively few procedures are performed per year, warn US investigators. The researchers found that in hospitals in which 22 or fewer minimally invasive pancreaticoduodenectomies (MPDs) were performed per year, the rate of complications […]
Read MoreA wide range of pre-existing psychiatric and behavioural conditions and the use of psychoactive drugs could be important risk factors leading to long-term use of opioid pain medications, according to a study published in the journal Pain. Using a nationwide insurance database, researchers identified 10.3 million patients who filed insurance claims for opioid prescriptions between […]
Read MoreAuthors: Toyoaki Maruta et al BMC Anesthesiol. 2016;16(110) A Prospective Randomised Single-Centre Study Background: Remifentanil is an effective drug for protecting against adverse haemodynamic responses to tracheal intubation. We compared the haemodynamic responses during anaesthesia induction between continuous intravenous (IV) infusion and two bolus injections of remifentanil. Methods: This prospective, randomised, open-label, single-centre study included patients with American […]
Read MoreAuthors: Erin J. Aiello Bowles, MPH et al J Am Geriatr Soc. 2016;64(3):602-607. Objectives: To evaluate the associations between anesthesia and dementia or Alzheimer’s disease (AD) risk using prospectively collected data. Design: Cohort study. Participants: Community-dwelling members of the Adult Changes in Thought cohort aged 65 and older and free of dementia at baseline (N = 3,988). Measurements: Participants self-reported […]
Read MoreDeaths involving the opioid painkiller fentanyl more than doubled from 2013 to 2014, according to a report released by the Centers for Disease Control and Prevention’s National Center for Health Statistics (NCHS). The report provides a detailed picture of the drugs most frequently involved in drug overdose deaths in the United States and highlights the frequency of […]
Read MoreAuthors: R. L. Johnson et al Br J Anaesth. 2016;116(2):163-176. A Systematic Review of Comparative-Effectiveness Research Background: This systematic review evaluated the evidence comparing patient-important outcomes in spinal or epidural vs general anaesthesia for total hip and total knee arthroplasty. Methods: MEDLINE, Ovid EMBASE, EBSCO CINAHL, Thomson Reuters Web of Science, and the Cochrane Central Register of Controlled Trials from […]
Read MoreRepeated or lengthy use of general anesthetic and sedation drugs in infants, toddlers and pregnant women in their third trimester might damage children’s developing brains, the U.S. Food and Drug Administration warned this month. Upset that the warning about pregnant women was based solely on animal studies, the American College of Obstetricians and Gynecologists, or […]
Read MoreBy Will Boggs MD About one in 20 patients might be aware of sensory stimuli during anesthesia, a rate lower than previously reported, according to an international, multicenter study. “We were pleased that the incidence of connected consciousness after intubation was lower than we feared, but we must be cautious, given the low event rate, […]
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