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Uncategorized Published - 30 May, 2017    By - Dr Clemens
Clinical Judgment Is Not Reliable for Reducing Whole-body Computed Tomography Scanning after Isolated High-energy Blunt Trauma

Authors: Thomas Mistral, M.D. et al Anesthesiology 6 2017, Vol.126, 1116-1124. Background: The purpose of this study was to test the diagnostic performance of clinical judgment for the prediction of a significant injury with whole-body computed tomography scanning after high-energy trauma. Methods: The authors conducted an observational prospective study in a single level-I trauma center. Adult patients were […]

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Uncategorized Published - 30 May, 2017    By - Dr Clemens
The Effect of Fixation Technique on Continuous Interscalene Nerve Block Catheter Success: A Randomized, Double-Blind Trial

AUTHORS: Auyong, David B. MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 959–965 BACKGROUND: Continuous peripheral nerve blocks offer advantages over single-injection blocks, including extended analgesia and reduction in opioid consumption. These benefits require that the perineural catheter remain intact for the duration of the planned local anesthetic […]

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Uncategorized Published - 30 May, 2017    By - Dr Clemens
The Use of Ultrasound Guidance for Perioperative Neuraxial and Peripheral Nerve Blocks in Children: A Cochrane Review

AUTHORS: Guay, Joanne MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 948–958 BACKGROUND: Objectives were to determine whether the use of ultrasound guidance offers any clinical advantage in the performance of neuraxial or peripheral nerve blocks in children in terms of increasing the success rate or decreasing the […]

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Uncategorized Published - 30 May, 2017    By - Dr Clemens
Associations Between Impaired Cerebral Blood Flow Autoregulation, Cerebral Oxygenation, and Biomarkers of Brain Injury and Postoperative Cognitive Dysfunction in Elderly Patients After Major Noncardiac Surgery

AUTHORS: Goettel, Nicolai MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 934–942 BACKGROUND: Increasing evidence links postoperative cognitive dysfunction (POCD) to surgery and anesthesia. POCD is recognized as an important neuropsychological adverse outcome in surgical patients, particularly the elderly. This prospective cohort study aimed to investigate whether POCD […]

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Uncategorized Published - 30 May, 2017    By - Dr Clemens
Economic Evaluation of Pharmacologic Pre- and Postconditioning With Sevoflurane Compared With Total Intravenous Anesthesia in Liver Surgery: A Cost Analysis

AUTHORS: Eichler, Klaus MD, MPH et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 925–933 BACKGROUND: Pharmacologic pre- and postconditioning with sevoflurane compared with total IV anesthesia in patients undergoing liver surgery reduced complication rates as shown in 2 recent randomized controlled trials. However, the potential health economic consequences of […]

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Uncategorized Published - 29 May, 2017    By - Dr Clemens
Happy Memorial Day

We wish all of our readers and their families a fun and safe Memorial weekend.

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Uncategorized Published - 26 May, 2017    By - Dr Clemens
Analgesia and Sedation Requirements in Mechanically Ventilated Trauma Patients With Acute, Preinjury Use of Cocaine and/or Amphetamines

AUTHORS: Kram, Bridgette PharmD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 782–788 BACKGROUND: The purpose of this study was to determine whether mechanically ventilated trauma patients with a positive urine drug screen (UDS) for cocaine and/or amphetamines have different opioid analgesic and sedative requirements compared with similar patients […]

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Uncategorized Published - 26 May, 2017    By - Dr Clemens
Prediction of Opioid Analgesic Efficacy by Measurement of Pupillary Unrest

AUTHORS: Neice, Andrew E. MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 915–921 BACKGROUND: Pupillary unrest under ambient light (PUAL) is the fluctuation in pupil diameter in time around a mean value. PUAL is augmented by light and diminished by administration of opioids. We hypothesized that, because pupillary […]

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Uncategorized Published - 26 May, 2017    By - Dr Clemens
Transcutaneous Carbon Dioxide Measurements in Women Receiving Intrathecal Morphine for Cesarean Delivery: A Prospective Observational Study

AUTHORS: Bauchat, Jeanette R. MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 872–878 BACKGROUND: Neuraxial morphine is the most commonly used analgesic technique after cesarean delivery. The incidence of respiratory depression is reported to be very low (0%–1.2%) in this patient population as measured by pulse oximetry and […]

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Uncategorized Published - 26 May, 2017    By - Dr Clemens
Effect of a High-Rate Versus a Low-Rate Oxytocin Infusion for Maintaining Uterine Contractility During Elective Cesarean Delivery: A Prospective Randomized Clinical Trial

AUTHORS: Duffield, Adrienne MD et al Anesthesia & Analgesia: March 2017 – Volume 124 – Issue 3 – p 857–862 BACKGROUND: Oxytocin is routinely used as prophylaxis against uterine atony. During elective cesarean delivery (CD), an oxytocin bolus is used to initiate adequate uterine tone, followed by an oxytocin infusion to maintain uterine contractility. However, it […]

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