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Amitriptyline accounted for approximately 2 of 5 deaths from antidepressants. Death and serious outcomes resulting from overdose or poisoning from drugs used to treat depression more than doubled during the last decade and a half, found a recent study, with amitriptyline topping the list. Fatal cases overall increased by 32%, and amitriptyline accounted for approximately […]
Read MoreAUTHORS: Enneking, F. Kayser MD et al Anesthesia & Analgesia: June 2017 – Volume 124 – Issue 6 – p 1957–1962 BACKGROUND: The purpose of this study was to validate a patient-centered anesthesia triage system (PCATS) by examining its association with, and predictive value of, ASA physical status (PS) classification. ASA PS classification is a widely […]
Read MoreDespite the common use of opioid analgesics in the management of chronic pain, no factors have been identified that could predict optimal efficacy of these agents. A study published in the March 2017 issue of Pain showed that psychosocial variables such as depression and anxiety predict the response to morphine analgesia in patients with low back pain […]
Read MoreAUTHORS: Onwochei, Desire N. MBBS BSc (Hons), FRCA et al Anesthesia & Analgesia: February 28, 2017 BACKGROUND: The use of phenylephrine as the first-line agent for prevention and treatment of maternal hypotension during cesarean delivery (CD) may reduce cardiac output, posing a theoretical risk to mother and fetus. Norepinephrine has been suggested as a potential alternative, […]
Read MoreAspiration of Baker’s cysts under ultrasound and fluoroscopic guidance followed by a therapeutic injection of methylprednisolone and bupivacaine reduces symptoms in most patients, according to a study presented here at the 2017 Annual European Congress of Radiology (ECR). Judita Laurinkiene, MD, University Hospital, Waterford, Ireland, and colleagues reviewed outcomes in 14 consecutive patients who underwent […]
Read MoreUp to 1 in 5 children suffer from migraine, and the risk for migraine increases from childhood to adolescence. Children with persistent asthma are at increased risk for migraine, and treatment with anti-asthma or anti-allergy medication may lower this risk, according to a study published in Headache.1 Up to 1 in 5 children suffer from migraine, […]
Read MoreAUTHOR: Tandon, Kanwarpreet MD et al Anesthesia & Analgesia: February 24, 2017 BACKGROUND: Colonoscopy quality is directly related to the bowel preparation. It is well established that bowel preparations are improved when at least part of the laxative is ingested on the day of the procedure. However, there is concern that this can result in higher […]
Read MoreAUTHORS: Kim, Tae Kyong MD et al Anesthesia & Analgesia: February 24, 2017 BACKGROUND: In patients with cervical immobilization, jaw thrust can cause cervical spine movement. Concurrent use of a laryngoscope may facilitate lightwand intubation, allowing midline placement and free movement of the lightwand in the oral cavity without jaw thrust. We compared the effects of […]
Read MoreAUTHORS: Bronsert, Michael R. PhD, MS et al Anesthesia & Analgesia: May 2017 – Volume 124 – Issue 5 – p 1476–1483 BACKGROUND: Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the […]
Read MoreA bioimpedance respiratory monitor seems to be carving out a niche for itself in perioperative monitoring. A group of Texas researchers has found that this novel technology (ExSpiron, Respiratory Motion Inc.) allows clinicians to adjust total IV anesthesia (TIVA) to minute ventilation in outpatient GI procedures, thereby preventing potential episodes of inadequate ventilation. “Death or […]
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