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New pilot study finds that Theranica’s electrical stimulation device, Nerivio Migra, is able to reduce migraine pain better than sham stimulation. The device is worn on the arm. Interviews with Brian Grosberg, MD, and Michael Marmura, MD Electrical stimulation has shown promise in the treatment of migraines and one device worn on the forehead, the […]
Read MoreAuthors: Johanna M. Lee, A.B. et al Anesthesiology published on June 29, 2017. Background: In adults, frontal electroencephalogram patterns observed during propofol-induced unconsciousness consist of slow oscillations (0.1 to 1 Hz) and coherent alpha oscillations (8 to 13 Hz). Given that the nervous system undergoes significant changes during development, anesthesia-induced electroencephalogram oscillations in children may differ from […]
Read MoreCurrent recommendations for outcome measures in clinical trials for chronic pain were outlined. Standardized and clinically meaningful outcome measures in clinical trials in chronic pain may enhance efforts to develop effective treatments for chronic pain patients. Diane Flynn, MD, MPH, from Madigan Army Medical Center, outlined the current recommendations for outcome measures in clinical trials […]
Read MoreAuthors: Adler NE and Glymour M., JAMA Intern Med 2017 Jun 12; More than half of adults who didn’t complete high school had adverse CV events during their lifetimes. Educational attainment is associated with risk for cardiovascular disease (CVD), presumably as a marker or mediator of other traditional risk factors. To clarify the magnitude of this risk, […]
Read MoreAuthors: WJ., J Am Coll Cardiol 2017 May 16; 69:2393 A high rate of adverse events prompts the question of whether earlier intervention would improve outcomes. The authors of this international, four-site study examined longitudinal outcomes data on 305 patients (mean age, 73; 75% men) who were identified on baseline echocardiograms with moderate aortic stenosis (AS; defined […]
Read MoreAuthors: Edmond C. K. Li, M.D. et al Anesthesiology 7 2017, Vol.127, 204-205. To the Editor: We read the secondary analysis of the Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia II (ENIGMA II) trial for severe postoperative nausea and vomiting (PONV) with great interest.1 Because PONV remains an often-cited risk in using nitrous oxide,2 the […]
Read MoreUse of low-dose aspirin lowers the risk for preeclampsia among women determined to be at high risk during first-trimester screening, according to a study presented at a meeting of the Fetal Medicine Foundation and published in the New England Journal of Medicine. Over 1700 high-risk women with singleton pregnancies were randomized to receive 150-mg aspirin or […]
Read MoreIn small, uncomplicated skin abscesses, the addition of antibiotics to usual treatment improves short-term outcomes, a New England Journal of Medicine study finds. In a multicenter trial, researchers randomized almost 800 adults and children with single skin abscesses to one of three regimens after incision and drainage: clindamycin, trimethoprim-sulfamethoxazole (TMP-SMX), or placebo. Treatments were prescribed for 10 […]
Read MoreAuthors: Thomas M. Austin, M.D. et al Anesthesiology 7 2017, Vol.127, 195-196. To the Editor: We read with interest the article by Bulka et al.1 regarding the use of intraoperative nondepolarizing muscle relaxants (NDMRs) and their association with postoperative pneumonia. We commend them for increasing knowledge in an area that is exceedingly important. In this article, postoperative pneumonia […]
Read MoreAuthors: Melanie M. Liu, M.D. et al Anesthesiology 7 2017, Vol.127, 166-172. CHRONIC steroid therapy is a cornerstone treatment for many common conditions, including inflammatory bowel disease, rheumatologic disease, reactive airway disease, and immunosuppression for transplant recipients. Patients on chronic steroid therapy may develop secondary adrenal insufficiency that can manifest as full-blown adrenal crisis in the […]
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