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Author: Ronald J. Gordon, M.D., Ph.D. Anesthesiology 8 2017, Vol.127, 401. To the Editor: I read with interest the study published recently by Eikelboom et al.1 in Anesthesiology. Because venous thromboembolism (VTE) is infrequently discussed in the anesthesia literature and is the leading cause of preventable death in surgical patients, certain aspects of the publication by Eikelboom et al.1 merit […]
Read MoreExtended-release tramadol may help reduce withdrawal symptoms in patients being treated for opioid use disorder, according to a JAMA Psychiatry study partly funded by industry. Roughly 100 adults with opioid use disorder were stabilized with morphine for 7–10 days in a residential research facility. During the subsequent 7-day taper phase, they were randomized to receive clonidine, buprenorphine, […]
Read MoreAuthor: Michael C. Reade, M.B.B.S., D.Phil. Anesthesiology 8 2017, Vol.127, 398. To the Editor: In the November 2016 issue of Anesthesiology, Wu et al.1 reported the results of their randomized controlled trial of low-dose (0.1 µg kg−1 h−1, nontitrated) dexmedetomidine in 76 nonmechanically ventilated noncardiac surgery patients aged 65 yr or older (an off-label use), in which dexmedetomidine was […]
Read MoreAuthors: Haley Goucher Miranda, M.D. et al Anesthesiology 8 2017, Vol.127, 397-398. To the Editor: In November 2016’s issue of Anesthesiology, Wu et al., in their article “Low-dose Dexmedetomidine Improves Sleep Quality Pattern in Elderly Patients after Noncardiac Surgery in the Intensive Care Unit: A Pilot Randomized Controlled Trial,”1 demonstrated polysomnographic improvement in sleep in patients treated with […]
Read MoreAuthors: Josephine To, B.Pharm. et al Anesthesiology 8 2017, Vol.127, 317-325. Background: Preoperative anemia is a significant predictor of perioperative erythrocyte transfusion in elective arthroplasty patients. However, interactions with other patient and procedure characteristics predicting transfusion requirements have not been well studied. Methods: Patients undergoing elective primary total hip arthroplasty or total knee arthroplasty at a tertiary hospital […]
Read MoreAuthors: Kurt Ruetzler, M.D. et al Anesthesiology 8 2017, Vol.127, 307-316 Background: Supraglottic airway devices commonly are used for securing the airway during general anesthesia. Occasionally, intubation with an endotracheal tube through a supraglottic airway is indicated. Reported success rates for blind intubation range from 15 to 97%. The authors thus investigated as their primary outcome the […]
Read MoreAuthors: Allison J. Lee, M.D. et al Anesthesiology 8 2017, Vol.127, 241-249. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining […]
Read MoreAuthors: Johanna M. Lee, A.B. et al Anesthesiology 8 2017, Vol.127, 293-306. Background: In adults, frontal electroencephalogram patterns observed during propofol-induced unconsciousness consist of slow oscillations (0.1 to 1 Hz) and coherent alpha oscillations (8 to 13 Hz). Given that the nervous system undergoes significant changes during development, anesthesia-induced electroencephalogram oscillations in children may differ from those […]
Read MoreAuthors: Nada Sabourdin, M.D. et al Anesthesiology 8 2017, Vol.127, 284-292. Background: Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits in clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact of intraoperative pupillometry monitoring on perioperative opioid consumption in major gynecologic surgery. Methods: After […]
Read MoreAuthors: Sandra Funcke, M.D. et al Anesthesiology 8 2017, Vol.127, 272-283. Background: This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth Index (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, and bispectral index, with regard to diagnostic accuracy and prediction probability for nociceptive response. The primary endpoint was the correlation […]
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