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Uncategorized Published - 31 August, 2017    By - Dr Clemens
No Need to Wait 3 Minutes After Standing to Assess Orthostatic Hypotension

Thomas L. Schwenk, MD and Allan S. Brett, MD Reviewing Juraschek SP et al., JAMA Intern Med 2017 Jul 24; Blood pressure readings within 1 minute might be more useful in predicting fractures, falls, and other adverse events. According to a 2011 consensus statement, blood pressure (BP) measurement to assess orthostatic hypotension should be done “within 3 minutes […]

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Uncategorized Published - 31 August, 2017    By - Dr Clemens
Occipital Headaches and Neuroimaging in Children

Christopher B. Oakley, MD Reviewing Bear JJ et al., Neurology 2017 Aug 1; 89:469 A retrospective case analysis finds no association between occipital headache location and intracranial pathology. The International Classification of Headache Disorders (ICHD-3 beta) suggests that headaches localizing to the occipital region in children may be indicative of an intracranial process. This sentiment, however, is not […]

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Uncategorized Published - 31 August, 2017    By - Dr Clemens
Pupillometry-guided Intraoperative Remifentanil Administration versus Standard Practice Influences Opioid Use: A Randomized Study

Authors: Nada Sabourdin, M.D. et al Anesthesiology 8 2017, Vol.127, 284-292. Background: Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits in clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact of intraoperative pupillometry monitoring on perioperative opioid consumption in major gynecologic surgery. Methods: After […]

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Uncategorized Published - 31 August, 2017    By - Dr Clemens
Accuracy of Capillary and Arterial Whole Blood Glucose Measurements Using a Glucose Meter in Patients under General Anesthesia in the Operating Room

Authors: Brad S. Karon, M.D., Ph.D. et al Anesthesiology 9 2017, Vol.127, 466-474. Background: The aim of this study was to evaluate the use of a glucose meter with surgical patients under general anesthesia in the operating room. Methods: Glucose measurements were performed intraoperatively on 368 paired capillary and arterial whole blood samples using a Nova StatStrip (Nova […]

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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Reversal of Vecuronium-induced Neuromuscular Blockade with Low-dose Sugammadex at Train-of-four Count of Four: A Randomized Controlled Trial

Authors: László Asztalos, M.D. et al Anesthesiology 9 2017, Vol.127, 441-449. Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg. We investigated whether these doses of sugammadex can also reverse vecuronium at a similar level of block. Methods: Sixty-five patients were randomly assigned, and 64 were […]

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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Extubation Success Prediction in a Multicentric Cohort of Patients with Severe Brain Injury

Authors: Karim Asehnoune, M.D., Ph.D. et al Anesthesiology 8 2017, Vol.127, 338-346. Background: Patients with brain injury are at high risk of extubation failure. Methods: We conducted a prospective observational cohort study in four intensive care units of three university hospitals. The aim of the study was to create a score that could predict extubation success in patients […]

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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Validation of Innovative Techniques for Monitoring Nociception during General Anesthesia: A Clinical Study Using Tetanic and Intracutaneous Electrical Stimulation

Authors: Sandra Funcke, M.D. et al Anesthesiology 8 2017, Vol.127, 272-283. Background: This study compares the analgesic indices Analgesia Nociception Index (heart rate variability), Surgical Pleth Index (photoplethysmography), and pupillary dilatation, to heart rate, mean arterial pressure, and bispectral index, with regard to diagnostic accuracy and prediction probability for nociceptive response. The primary endpoint was the correlation […]

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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Association of Testosterone Replacement Therapy and the Incidence of a Composite of Postoperative In-hospital Mortality and Cardiovascular Events in Men Undergoing Noncardiac Surgery

Authors: Maged Y. Argalious, M.D., M.Sc., M.B.A., M.Ed., F.A.S.E. et Anesthesiology 9 2017, Vol.127, 457-465. Background: Whether patients on testosterone replacement therapy undergoing noncardiac surgery have an increased risk of postoperative in-hospital mortality and cardiovascular events remains unknown. We therefore sought to identify the impact of testosterone replacement on the incidence of a composite of postoperative in-hospital […]

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Uncategorized Published - 30 August, 2017    By - Dr Clemens
Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room

Authors: Matthieu Biais, M.D., Ph.D. et al Anesthesiology 9 2017, Vol.127, 450-456 Background: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of 250 ml crystalloid in mechanically […]

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Uncategorized Published - 29 August, 2017    By - Dr Clemens
Left Lateral Table Tilt for Elective Cesarean Delivery under Spinal Anesthesia Has No Effect on Neonatal Acid–Base Status: A Randomized Controlled Trial

Authors: Allison J. Lee, M.D. Background: Current recommendations for women undergoing cesarean delivery include 15° left tilt for uterine displacement to prevent aortocaval compression, although this degree of tilt is practically never achieved. We hypothesized that under contemporary clinical practice, including a crystalloid coload and phenylephrine infusion targeted at maintaining baseline systolic blood pressure, there would […]

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