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Two leading authorities in migraine management announced favorable results in separate trials targeting calcitonin gene-related peptide with mAb treatments for migraine pain. By Vicki Moore, PhD with Lawrence Robbins, MD Managing migraines may improve given the positive outcomes of two Phase 3 trials of monoclonal antibody migraine-preventive treatments directed against the calcitonin gene-related peptide (CGRP) and […]
Read MoreEdited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD More than 1 in 6 adults who survive revascularization for peripheral arterial disease have an unplanned readmission within 30 days, according to a study in the Annals of Internal Medicine. U.S. researchers used the Nationwide Readmissions Database from 2017 to identify nearly 62,000 patients who underwent […]
Read MoreAnesthesia published on Dec 5, 2017 Authors: S. R. Tasbihgou et al Summary Unintended accidental awareness during general anaesthesia represents failure of successful anaesthesia, and so has been the subject of numerous studies during the past decades. As return to consciousness is both difficult to describe and identify, the reported incidence rates vary widely. Similarly, […]
Read MoreAuthors: Tobias Kammerer, M.D. et al Anesthesiology 1 2018, Vol.128, 67-78. Background: The use of artificial colloids has declined in critical care, whereas they are still used in perioperative medicine. Little is known about the nephrotoxic potential in noncritically ill patients during routine surgery. The objective of this trial was to evaluate the influences of albumin 5% […]
Read MoreAuthors: Christopher Brasher, M.D. et al Anesthesiology 1 2018, Vol.128, 4-5. “Preterm infants have substantial intravenous therapeutic needs over prolonged periods of time.” HOW to best insert and maintain central venous catheters in small infants is a question of interest to all health professionals working in the field. The hospitalized small infant population is growing as […]
Read MoreWe want to wish all of our readers a very Merry Christmas and please be safe.
Read MoreEdited by David G. Fairchild, MD, MPH, and Jaye Elizabeth Hefner, MD While total opioid-related hospital admissions remained stable between 2000 and 2014, deaths from opioid-driven hospitalizations rose nearly fivefold, Health Affairs reports. A researcher examined nationally representative hospitalization data. He concludes that despite the stable rate of hospital admissions owing to opioids, the intensity of those admissions increased […]
Read MoreAuthor: Zirui Song Hospitals play an important role in caring for patients in the current opioid crisis, but data on the outcomes and composition of opioid-driven hospitalizations in the United States have been lacking. Nationally representative all-payer data for the period 1993–2014 from the National Inpatient Sample were used to compare the mortality rates and […]
Read MoreNonpharmacologic interventions improve outcomes. By Amy Karon Preventing delirium in the ICU doesn’t have to involve sophisticated medical interventions. Doubling the length of family visiting hours halved rates of ICU delirium, according to one study. And twice-daily occupational therapy cut the risk of ICU delirium even more dramatically when added to standard preventive measures, such as avoiding restraints […]
Read MoreEdited by Susan Sadoughi, MD Two humanized monoclonal antibodies seem effective in preventing migraine, according to two industry-conducted, phase III trials in the New England Journal of Medicine. The investigational treatments target the calcitonin gene-related peptide (CGRP) or its receptor; CGRP affects neuronal modulation of pain and vascular activity. In the first trial, researchers randomized nearly 1000 […]
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