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The rate of drug overdose deaths in the U.S. rose 21% from 2015 to 2016, reaching 20 per 100,000 population, according to new data from the CDC’s National Center for Health Statistics. Adults aged 25 to 54 had the highest overdose death rates, at roughly 35 per 100,000. Also of note: the overdose death rate […]
Read MorePatients with spastic arm paralysis from chronic cerebral injury like a stroke or trauma might benefit from a technique to route a nerve from the nonparalyzed side, suggests a small trial in the New England Journal of Medicine. Chinese researchers randomized 36 males to undergo 12 months of physical therapy either alone or with contralateral C7 […]
Read MoreAuthors: Arshi, Armin MD et al JBJS: December 06, 2017 – Volume 99 – Issue 23 – p 1978–1986 Background: As concerns regarding health-care expenditure in the U.S. remain at the national forefront, outpatient arthroplasty is an appealing option for carefully selected patient populations. The purpose of this study was to determine the nationwide trends and complication […]
Read MoreAUTHORS: Biais, Matthieu MD, PhD et al Anesthesia & Analgesia: December 2017 – Volume 125 – Issue 6 – p 1889–1895 BACKGROUND: End-expiratory occlusion test (EEOT) has been proposed to predict fluid responsiveness in mechanically ventilated intensive care unit patients. The utility of this test during low-tidal-volume ventilation remains uncertain. This study aimed to determine whether hemodynamic […]
Read MoreA special report by University of Pennsylvania health care economists suggests the health care industry suffers from an “acute” problem with “deceptive, misleading, unsubstantiated, and foolish statements”—which they refer to as health care “BS.” Cheat sheet series: Evidence-based practice 101 From Theranos to Watson: BS is everywhere In a special report, Wharton School health care […]
Read MoreAuthors: Stephen J. Raithel, B.A. et al Anesthesiology published December, 2017. Background: Peripheral nociceptors expressing the ion channel transient receptor potential cation channel, subfamily V, member 1, play an important role in mediating postoperative pain. Signaling from these nociceptors in the peri- and postoperative period can lead to plastic changes in the spinal cord and, when controlled, […]
Read MoreAuthors: Sheila Riazi, M.Sc., M.D. et al Anesthesiology 1 2018, Vol.128, 168-180 This article reviews advancements in the genetics of malignant hyperthermia, new technologies and approaches for its diagnosis, and the existing limitations of genetic testing for malignant hyperthermia. It also reviews the various RYR1-related disorders and phenotypes, such as myopathies, exertional rhabdomyolysis, and bleeding disorders, and […]
Read MoreBy Elizabeth Snell An AMA study found that 83 percent of US physicians experienced a cybersecurity attack, with healthcare phishing being the leading cause. Healthcare organizations should consider increasing their cybersecurity measures as 83 percent of physicians report they have experienced a cybersecurity attack, according to research from Accenture and the American Medical Association (AMA). Approximately 1,300 US […]
Read MoreN Engl J Med 2017; 377:2192-2193 November 30, 2017 To the Editor: We present the case of a person whose presumed code-status preference led him to tattoo “Do Not Resuscitate” on his chest. Paramedics brought an unconscious 70-year-old man with a history of chronic obstructive pulmonary disease, diabetes mellitus, and atrial fibrillation to the emergency […]
Read MoreTargeted Genotyping Identifies Susceptibility Locus in Brain-derived Neurotrophic Factor Gene for Chronic Postsurgical Pain Authors: Yuanyuan Tian, B.Med., M.Med., Ph.D. et al Anesthesiology published December, 2017. Background: The purpose of this study was to evaluate the association between single-nucleotide polymorphisms and chronic postsurgical pain. Methods: Using GoldenGate genotyping assays, we genotyped 638 polymorphisms within 54 pain-related genes in […]
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