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Uncategorized Published - 15 January, 2018    By - Dr Clemens
Period-dependent Associations between Hypotension during and for Four Days after Noncardiac Surgery and a Composite of Myocardial Infarction and Death: A Substudy of the POISE-2 Trial

Authors: Daniel I. Sessler, M.D. et al Anesthesiology 2 2018, Vol.128, 317-327. Background: The relative contributions of intraoperative and postoperative hypotension to perioperative morbidity remain unclear. We determined the association between hypotension and a composite of 30-day myocardial infarction and death over three periods: (1) intraoperative, (2) remaining day of surgery, and (3) during the initial four […]

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Uncategorized Published - 15 January, 2018    By - Dr Clemens
Impact of a Novel Multiparameter Decision Support System on Intraoperative Processes of Care and Postoperative Outcomes

Authors: Sachin Kheterpal, M.D., M.B.A. et al Anesthesiology 2 2018, Vol.128, 272-282. Background: The authors hypothesized that a multiparameter intraoperative decision support system with real-time visualizations may improve processes of care and outcomes. Methods: Electronic health record data were retrospectively compared over a 6-yr period across three groups: experimental cases, in which the decision support system was used […]

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Uncategorized Published - 15 January, 2018    By - Dr Clemens
Defining the Intrinsic Cardiac Risks of Operations to Improve Preoperative Cardiac Risk Assessments

Authors: Jason B. Liu, M.D., M.S. et al Anesthesiology 2 2018, Vol.128, 283-292. Background: Current preoperative cardiac risk stratification practices group operations into broad categories, which might inadequately consider the intrinsic cardiac risks of individual operations. We sought to define the intrinsic cardiac risks of individual operations and to demonstrate how grouping operations might lead to imprecise […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study—A Prospective Randomized Trial)

AUTHORS: McCann, M. E. MD, MPH et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 837–845 BACKGROUND: The General Anesthesia compared to Spinal anesthesia (GAS) study is a prospective randomized, controlled, multisite, trial designed to assess the influence of general anesthesia (GA) on neurodevelopment at 5 years of age. A secondary […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
Patients Undergoing Orthotopic Liver Transplantation Require Lower Concentrations of the Volatile Anesthetic Sevoflurane

AUTHORS: Baron-Stefaniak, Joanna MD et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 783–789 BACKGROUND: Sevoflurane is a volatile anesthetic commonly used to maintain anesthesia in patients with end-stage liver disease (ESLD) undergoing orthotopic liver transplantation (OLT). Growing evidence suggests that patients with ESLD have decreased anesthetic requirements compared to patients […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
Rehab Expert: Pain Patients Denied Needed Opioids in Palliative Care

David, a 38-year-old father of four and five-year survivor of fungal meningitis, experiences the long-term effects of contaminated epidural injections that have left him with headaches, visual disturbances, tinnitus, adhesive arachnoiditis and fibromyalgia. His story exemplifies the gap between state and federal health care laws and treatment protocols for those with chronic pain requiring high-dose […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
IARS Consensus Statement Addresses Neuromuscular Monitoring

In an effort to improve the use and safety of neuromuscular monitoring, the International Anesthesia Research Society recently published a consensus statement on its use in the perioperative setting (Anesth Analg 2017 Nov 30. [Epub ahead of print]). The statement includes several recommendations laid out by a team of physician experts on the proper use […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
Bariatric Surgery Linked to Prolonged Post-op Opioid Use

Roughly one in 12 bariatric patients who did not take opioid pain medications until their weight loss surgery, or the month before it, reported that they are still using prescription opioids one year postoperatively, a rate of prolonged use that is more than 45% higher than people who underwent other general surgery procedures. Among all […]

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Uncategorized Published - 12 January, 2018    By - Dr Clemens
A Comparison Between the Conventional and the Laryngoscope-Assisted Lightwand Intubation Techniques in Patients With Cervical Immobilization: A Prospective Randomized Study

AUTHORS: Kim, Eugene MD et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 854–859 BACKGROUND: Positioning of a lightwand in the midline of the oral cavity can be challenging in patients with cervical immobilization. Direct laryngoscopy may permit the lightwand tip to more easily access the glottic opening. We tested our […]

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Uncategorized Published - 11 January, 2018    By - Dr Clemens
Interest of Urinary [TIMP-2] × [IGFBP-7] for Predicting the Occurrence of Acute Kidney Injury After Cardiac Surgery: A Gray Zone Approach

AUTHORS: Finge, Toufic MD et al Anesthesia & Analgesia: September 2017 – Volume 125 – Issue 3 – p 762–769 BACKGROUND: This study assessed the ability of 3-hour postoperative urinary tissue inhibitor of metalloproteinases-2 × insulin-like growth factor binding protein-7 ([TIMP-2] × [IGFBP-7]) to predict postoperative acute kidney injury (AKI) in patients undergoing cardiopulmonary bypass during cardiac […]

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