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Uncategorized Published - 10 April, 2018    By - Dr Clemens
No Significant Association Between the Transfusion of Small Volumes of Leukocyte-Depleted Red Blood Cells and Mortality Over 7 Years of Follow-up in Patients Undergoing Cardiac Surgery: A Propensity Score Matched Analysis

AUTHORS: Koster, Andreas et al Anesthesia & Analgesia: October 19, 2017 BACKGROUND: The impact of red blood cell (RBC) transfusion on long-term clinical outcome is controversial. METHODS: We prospectively recorded follow-up data of 6124 cardiac surgical patients who received no transfusion (RBC− group) or 1–2 units of leukocyte-depleted RBC (RBC+ group) at our institution. The primary end point […]

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Uncategorized Published - 9 April, 2018    By - Dr Clemens
US homes need Narcan to aid in opioid overdose epidemic, surgeon general advises

Amid an opioid crisis that is claiming tens of thousands of lives each year, the U.S. surgeon general on Thursday urged Americans to start carrying a drug that reverses overdoses. It marks the first time in 13 years that the nation’s top doctor has issued a public health advisory. Speaking at the National Rx Drug […]

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Uncategorized Published - 9 April, 2018    By - Dr Clemens
Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors

British Journal of Anesthesia March 18 Authors: S.M. Weinstein et al Background Postoperative delirium continues to pose major clinical difficulties. While unmodifiable factors (e.g. age and comorbidity burden) are commonly studied risk factors for delirium, the role of modifiable factors, such as anaesthesia type and commonly used perioperative medications, remains understudied. This study aims to […]

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Uncategorized Published - 9 April, 2018    By - Dr Clemens
The Influence of Age on Sensitivity to Dexmedetomidine Sedation During Spinal Anesthesia in Lower Limb Orthopedic Surgery

Authors: Xu, Bo MD et al Anesthesia & Analgesia: December 2017 – Volume 125 – Issue 6 – p 1907–1910 To investigate the influence of age on sensitivity to dexmedetomidine sedation in adult patients, we selected 79 patients scheduled for lower limb orthopedic surgery under spinal anesthesia to identify the dexmedetomidine ED50 for adequate sedation among different […]

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Uncategorized Published - 9 April, 2018    By - Dr Clemens
ACE Question

ASA Monitor 4 2018, Vol.82, 43. Which of the following has a greater likelihood of being present in a child with laryngotracheobronchitis (croup) than in a child with epiglottitis? Croup is a viral illness most commonly attributed to the following infectious agents: Croup, the most common infectious cause of stridor in children, generally begins as an upper-respiratory tract […]

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Uncategorized Published - 9 April, 2018    By - Dr Clemens
Current Ventilator and Oxygen Management during General Anesthesia: A Multicenter, Cross-sectional Observational Study

Authors: Satoshi Suzuki, M.D., Ph.D. et al Anesthesiology March 2018. Background: Intraoperative oxygen management is poorly understood. It was hypothesized that potentially preventable hyperoxemia and substantial oxygen exposure would be common during general anesthesia. Methods: A multicenter, cross-sectional study was conducted to describe current ventilator management, particularly oxygen management, during general anesthesia in Japan. All adult patients (16 […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Comparison of Two Major Perioperative Bleeding Scores for Cardiac Surgery Trials: Universal Definition of Perioperative Bleeding in Cardiac Surgery and European Coronary Artery Bypass Grafting Bleeding Severity Grade

Authors: Justyna Bartoszko, M.D. et al Anesthesiology March 2018. Background: Research into major bleeding during cardiac surgery is challenging due to variability in how it is scored. Two consensus-based clinical scores for major bleeding: the Universal definition of perioperative bleeding and the European Coronary Artery Bypass Graft (E-CABG) bleeding severity grade, were compared in this substudy of […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Amisulpride Prevents Postoperative Nausea and Vomiting in Patients at High Risk: A Randomized, Double-blind, Placebo-controlled Trial

Authors: Peter Kranke, M.D., M.B.A. et al Anesthesiology published on March 2018 Background: Postoperative nausea and vomiting causes distress for patients and can prolong care requirements. Consensus guidelines recommend use of multiple antiemetics from different mechanistic classes as prophylaxis in patients at high risk of postoperative nausea and vomiting. The prophylactic efficacy of the dopamine D2/D3 antagonist amisulpride […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Effects of Prone Positioning on Transpulmonary Pressures and End-expiratory Volumes in Patients without Lung Disease

Authors: Abirami Kumaresan, M.D. et al Anesthesiology Newly Published on March 8, 2018. Background: The effects of prone positioning on esophageal pressures have not been investigated in mechanically ventilated patients. Our objective was to characterize effects of prone positioning on esophageal pressures, transpulmonary pressure, and lung volume, thereby assessing the potential utility of esophageal pressure measurements in […]

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Uncategorized Published - 6 April, 2018    By - Dr Clemens
Opioids No Better Than Nonopioids for Easing Common Types of Chronic Pain

Author: Lorenzo Di Francesco, MD, FACP, FHM Opioids are not better than nonopioid drugs for relieving back pain or pain related to hip or knee osteoarthritis, a JAMA study finds. Nearly 250 patients with moderate-to-severe chronic back pain or hip or knee osteoarthritis pain were randomized to receive either opioids or nonopioids. In the opioid group, patients […]

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