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The presence of diabetes — both type 1 and type 2 — may be associated with a reduced risk for migraine, according to a long-term nationwide Norwegian study published in Cephalalgia. Study investigators evaluated patients with type 1 diabetes (n=7883) and type 2 diabetes (n=93,600) who were included in the Norwegian Prescription Database, the Norwegian National […]
Read MoreIntravenous saline use causes more kidney complications and decreases survival rates compared with balanced crystalloids (lactated Ringer’s solution or Plasma-Lyte A [Baxter]), according to researchers at Vanderbilt University Medical Center, in Nashville, Tenn. The researchers found that patients experience better outcomes when given the balanced crystalloids, which most closely resemble components of the liquid part […]
Read MoreLondon-listed pharmaceutical group Hikma (HIK.L) said it was increasing its supply of hydromorphone to U.S. hospitals to help ease a shortage of injectable opioids used to treat patients. Injectable opioid painkillers, which hospitals use to manage pain after operations and in terminal illness, have been in short supply for more than a year largely due […]
Read MoreAUTHORS: Levin, Phillip D., MB BChir et al Anesthesia & Analgesia: March 1, 2018 – Procalcitonin (PCT) measurement has been proposed to direct antibiotic use. We examined whether repeated PCT measurements (0, 6, and/or 12 hours) versus the initial measurement only (time 0) increased the sensitivity and specificity of PCT for diagnosing infection in intensive care […]
Read MoreAUTHORS: Yan, Haiya, MD et al Anesthesia & Analgesia: March 1, 2018 – BACKGROUND: Autologous transfusion of intraoperative cell salvage blood may be a potential method to decrease the need for allogeneic packed red blood cell transfusions after cesarean delivery, although there are limited data on the benefits of this method. This study evaluated the implementation of […]
Read MoreAUTHORS: Lappen, Justin R., MD et al Anesthesia & Analgesia: August 2018 – Volume 127 – Issue 2 – p 457–464 BACKGROUND: Narrow pulse pressure has been demonstrated to indicate low central volume status. In critically ill patients, volume status can be qualitatively evaluated using Doppler velocimetry to assess hemodynamic changes in the carotid artery in response […]
Read MoreAUTHORS: Ruetzler, Kurt, MD et al Anesthesia & Analgesia: March 1, 2018 BACKGROUND: Laboratory testing is a common component of preanesthesia evaluation and is designed to identify medical abnormalities that might otherwise remain undetected. While blood testing might optimally be performed shortly before surgery, it is often done earlier for practical reasons. We tested the hypothesis that […]
Read MoreThe Food and Drug Administration (FDA) has approved Apadaz (benzhydrocodone and acetaminophen; KemPharm) for the short-term (≤14 days) management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Apadaz is an immediate-release combination of benzhydrocodone, a prodrug of hydrocodone, and acetaminophen (APAP). Benzhydrocodone is chemically inert, however, once ingested, […]
Read MoreRecommendations for the perioperative use of buprenorphine during interventional pain procedures, including best practices for perioperative tapering of the drug, were recently published in Pain Physician. The researchers based their buprenorphine recommendations on an analysis of 12 studies in the literature researching buprenorphine. The recommendations include suggestions for tapering or continuing use of the drug in the […]
Read MoreThe American Society of Anesthesiologists (ASA) has offered recommendations for Congress to address the opioid epidemic through the Centers for Medicare & Medicaid Services programs. The recommendations include increasing funding for research, adding coverage for nonopioid therapies, and providing congressional support for educational programs for perioperative opioid-sparing practices. “With a unique understanding of the intricacies […]
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