Anesthesiology

Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks

Authors: Turan A et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005869 SummaryThis multicenter randomized controlled trial (the CLEVELAND Trial) evaluated whether liposomal bupivacaine provides superior or prolonged analgesia compared with plain bupivacaine or saline when used in single-injection, four-quadrant transversus abdominis plane (TAP) blocks for major abdominal surgery. Given widespread use of liposomal bupivacaine […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index

Authors: Hussain N et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005876 SummaryThis systematic review evaluated the statistical robustness of randomized controlled trials assessing spinal cord stimulation (SCS for chronic pain using the fragility index (FI). While SCS has gained wide adoption based on statistically significant trial outcomes, the fragility index provides a complementary lens […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
The role of the dorsomedial periaqueductal gray glutamatergic neurons in promoting arousal under multiple general anesthetics in mice

Authors: Tong L et al. Journal: Anesthesiology, December 15, 2025. DOI: 10.1097/ALN.0000000000005903 SummaryThis preclinical study investigated the role of glutamatergic neurons in the dorsomedial periaqueductal gray (dmPAG) as a shared neural substrate regulating arousal and emergence across multiple general anesthetics. Although general anesthetics differ in molecular targets, the authors hypothesized that convergent brainstem circuitry may […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
756 hospitals at risk of closure, state by state

Author: Molly Gamble Becker’s Hospital Review Seven hundred fifty-six rural U.S. hospitals are at risk of closure due to financial problems, with more than 40% of those hospitals at immediate risk of closure. The counts are drawn from the Center for Healthcare Quality and Payment Reform’s most recent analysis, based on hospitals’ latest cost reports submitted […]

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Anesthesiology Published - 12 January, 2026    By - Dr Clemens
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications

Authors: Wachtendorf LJ et al. Journal: Anesthesiology, December 4, 2025. DOI: 10.1097/ALN.0000000000005880 SummaryThis large retrospective cohort study evaluated how the introduction of sugammadex influenced intraoperative rocuronium dosing practices and whether these changes affected postoperative respiratory complications. Because sugammadex enables rapid reversal of even deep neuromuscular blockade, concerns have emerged that its availability may encourage higher […]

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Anesthesiology Published - 12 January, 2026    By - Dr Clemens
The anesthesia battles that ASCs won in 2025

Author: Francesca Mathewes Becker’s ASC Review Workforce shortages, reimbursement declines and costly inefficiencies were some of the biggest anesthesia-related issues for ASC leaders in 2025. While many of these issues will persist into 2026, here are the wins that ASC leaders shared with Becker’s throughout the last year: Staffing shortages The projected shortage of anesthesiologists by […]

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Anesthesiology Published - 12 January, 2026    By - Dr Clemens
Saccade tasks: A non-invasive approach for predicting postoperative delirium in elderly arthroplasty patients

Authors: Kang M et al. Journal: Anesthesiology, December 4, 2025. DOI: 10.1097/ALN.0000000000005875 SummaryThis prospective observational study evaluated whether preoperative saccadic eye movement tasks can serve as a noninvasive and accurate predictor of postoperative delirium (POD) in elderly patients undergoing arthroplasty. Given the limitations of traditional cognitive screening tools and invasive biomarker testing, the authors sought […]

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Anesthesiology Published - 12 January, 2026    By - Dr Clemens
Pain as a Driver of Myocardial Injury in Hip Fracture Patients: A Hip Fracture Accelerated Surgical Treatment and Care Track (HIP ATTACK) Trial Secondary Analysis

Authors: Khan JS et al. Journal: Anesthesiology, December 4, 2025. DOI: 10.1097/ALN.0000000000005818 SummaryThis prespecified secondary analysis of the HIP ATTACK randomized trial examined whether perioperative pain severity is associated with myocardial injury and ischemic events in patients undergoing hip fracture surgery. Hip fracture patients are particularly vulnerable to cardiovascular complications, and uncontrolled pain may provoke […]

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Anesthesiology Published - 12 January, 2026    By - Dr Clemens
Effects of repeated early life anesthesia exposure on visual system development in mice.

Authors: Seillier C et al. Journal: Anesthesiology, December 4, 2025. DOI: 10.1097/ALN.0000000000005879 SummaryThis preclinical study examined the effects of repeated early-life exposure to general anesthesia on visual system development in mice and explored the role of tissue-type plasminogen activator (tPA) as a potential mechanistic mediator. Given ongoing concerns about neurodevelopmental consequences of pediatric anesthesia—and prior […]

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Anesthesiology Published - 9 January, 2026    By - Dr Clemens
Critical Closing and Tissue Perfusion Pressures in Sepsis—Implications for Risk Stratification

Authors: Wang J-Y et al. Journal: Anesthesiology, December 5, 2025. DOI: 10.1097/ALN.0000000000005881 SummaryThis large retrospective cohort study evaluated whether critical closing pressure (Pcc) and tissue perfusion pressure (TPP) improve prognostication and risk stratification in patients with sepsis beyond mean arterial pressure (MAP) alone. While MAP is the cornerstone hemodynamic target in sepsis management, it does […]

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