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Uncategorized Published - 4 October, 2022    By - Dr Clemens
Respiratory Effects of the Atypical Tricyclic Antidepressant Tianeptine in Human Models of Opioid-induced Respiratory Depression

Authors: Hyke Algera, M.D. et al  Anesthesiology October 2022, Vol. 137, 446–458. Background Animal data suggest that the antidepressant and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor modulator tianeptine is able to prevent opioid-induced respiratory depression. The hypothesis was that oral or intravenous tianeptine can effectively prevent or counteract opioid-induced respiratory depression in humans. Methods Healthy male and female volunteers […]

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Uncategorized Published - 4 October, 2022    By - Dr Clemens
Bedside Diagnosis of Pulmonary Embolism Using Electrical Impedance Tomography

Authors: Kuk, Won-Jun MD; Wright, Nathan R. MD A & A Practice: July 2022 – Volume 16 – Issue 7 – p e01606 Abstract Electrical impedance tomography (EIT) is an emerging imaging modality that can be used to diagnose ventilatory and intrathoracic perfusion mismatches in unstable patients at the bedside. We present a case of […]

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Uncategorized Published - 4 October, 2022    By - Dr Clemens
Intravenous Amisulpride Does Not Meaningfully Prolong the QTc Interval at Doses Effective for the Management of Postoperative Nausea and Vomiting

Authors: Fox, Gabriel M. MB BChir et al  Anesthesia & Analgesia: January 2021 – Volume 132 – Issue 1 – p 150-159 Background:  Postoperative nausea and vomiting (PONV) are significant issues in surgical patients, and additional treatment options are needed. Dopaminergic antiemetics have been popular for their efficacy, but their use has been limited by safety […]

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Uncategorized Published - 4 October, 2022    By - Dr Clemens
Percutaneous Radiofrequency Ablation for Trigeminal Neuralgia Management

DG Journal Club Authors: André Marques Mansano et al Pain Med. 2022 Aug 27 Trigeminal neuralgia, considered by many the worst pain that humankind can experience, has been called “the suicide disease.” Neuroablative procedures are good options when conservative treatment fails to promote pain relief or in those whose side effects are unbearable. The objective […]

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Uncategorized Published - 4 October, 2022    By - Dr Clemens
Everything you need to know about crystal meth

Authors: Yvette Brazier MedicalNewsToday Crystal meth, or methamphetamine, is a stimulant drug that carries a high risk for physical dependence. In the United States, a different formulation of methamphetamine called Desoxyn is available by prescription to treat attention deficit hyperactivity disorder (ADHD). Crystal meth has a number of street names, including ice and glass. It […]

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