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Anesthesiology Published - 3 September, 2025    By - Dr Clemens
Superficial parasternal intercostal plane blocks with liposomal bupivacaine did not significantly reduce opioid use after cardiac surgery

Author: Simon ER, et al. BMJ Journal Regional Anesthesia & Pain Medicine, Published online August 24, 2025. doi:10.1136/rapm-2025-106952 This prospective, randomized, double-blind controlled trial investigated whether bilateral superficial parasternal intercostal plane (SPIP) blocks with liposomal bupivacaine could reduce postoperative opioid consumption after cardiac surgery via median sternotomy. One hundred patients undergoing elective CABG or valve […]

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Anesthesiology Published - 3 September, 2025    By - Dr Clemens
The missing skillset from anesthesia’s workforce

Author: Francesca Mathewes Becker’s ASC Review Nonoperating room anesthesia cases are expected to account for more than 50% of all anesthesia cases in the next decade, according to a report by the American Hospital Association and the American Society of Anesthesiologists. As the demand for anesthesia services continues to shift outside of the hospital setting and into […]

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Anesthesiology Published - 3 September, 2025    By - Dr Clemens
Microcirculation Under the Magnifying Glass: When the Analysis Does Go Wrong

Author: Unknown (Letter to the Editor) Anesthesia & Analgesia, 2025. This letter critiques a clinical trial by Coeckelenbergh et al. comparing standard goal-directed fluid therapy (GDFT) with software-assisted fluid management (AFM) in high-risk surgical patients. While the trial reported that AFM improved cardiac output, perfusion, and microvascular flow, the authors raise several methodological concerns. They […]

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Anesthesiology Published - 3 September, 2025    By - Dr Clemens
Evaluation of a web app-based music intervention on pain during wound closure in the emergency department

Author: Charron M, et al. Anaesthesia Critical Care & Pain Medicine, 2025. doi:10.1016/j.accpm.2025.101545 This multicenter randomized, open-label trial evaluated the impact of a web app-based music intervention (Music Care®) during wound suturing in the emergency department. A total of 170 patients were randomized to receive music via the app or standard care. The primary endpoint […]

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Anesthesiology Published - 3 September, 2025    By - Dr Clemens
Comparative Electroencephalographic Profile of a New Anesthetic and Anticonvulsant That Is Selective for the GABAAR Slow Receptor Subtype

Author: Maciver MB, et al. Anesthesia & Analgesia 141(2):412-421, August 2025. doi:10.1213/ANE.0000000000007178 This preclinical study compared the electroencephalography (EEG) effects of propofol, a broad-spectrum GABAAR agonist, with a newly developed selective GABAAR-slow agonist, KSEB 01-S2. Male rats were implanted with subcranial EEG electrodes and given either propofol or KSEB 01-S2. EEG recordings were analyzed around […]

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