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Uncategorized Published - 1 November, 2022    By - Dr Clemens
Sex Differences in In-Hospital Mortality After Open Cardiac Valve Surgery

AUTHORS: Bradley, Stephanie MD, MPH et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 944-953 BACKGROUND: Cardiac valvular disease affects millions of people worldwide and is a major cause of morbidity and mortality. Female patients have been shown to experience inferior clinical outcomes after nonvalvular cardiac surgery, but recent data […]

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Uncategorized Published - 1 November, 2022    By - Dr Clemens
Pilot Findings of Pharmacogenomics in Perioperative Care

AUTHORS: Truong, Tien M. PharmD, PhD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 929-940 BACKGROUND: Pharmacogenomics, which offers a potential means by which to inform prescribing and avoid adverse drug reactions, has gained increasing consideration in other medical settings but has not been broadly evaluated during perioperative care. […]

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Uncategorized Published - 1 November, 2022    By - Dr Clemens
The Next Viral Pandemic: Not a Question of If, But When and How

Author: Vetter, Thomas R. MD, MPH Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 900-902 “Those who cannot remember the past are condemned to repeat it.” —Jorge Agustín Nicolás Ruiz de Santayana y Borrás, known in English as George Santayana (1863–1952), Spanish-American philosopher, essayist, poet, and novelist In early January […]

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Uncategorized Published - 1 November, 2022    By - Dr Clemens
Characterization of 2 Different Prothrombin Complex Concentrates by Different Hemostatic Assays in an In Vitro Hemodilution Model

AUTHORS: Infanger, Lukas MD et al  Anesthesia & Analgesia: November 2022 – Volume 135 – Issue 5 – p 1031-1040 BACKGROUND: Viscoelastically guided coagulation factor concentrate-based algorithms for the treatment of trauma-induced coagulopathy include the administration of prothrombin complex concentrates (PCCs). However, the exact role of PCC preparations in this context is a matter of debate. […]

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Uncategorized Published - 31 October, 2022    By - Dr Clemens
Total Intravenous Anesthesia Versus Inhaled Sevoflurane in Obstructive Sleep Apnea Surgery

AUTHORS: Leonard E Estephan et al Laryngoscope. 2022 Oct 14 OBJECTIVE Specific guidelines regarding an optimal general anesthesia (GA) approach to obstructive sleep apnea (OSA) patients remain undefined. Literature comparing the efficacy of total intravenous anesthesia (TIVA) and inhalational anesthesia in this population is sparse. We hypothesize that OSA patients receiving TIVA will experience reduced […]

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