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Uncategorized Published - 2 December, 2022    By - Dr Clemens
CRPS and Non-Conventional Pharmacological Therapies

Authors: Tran D, Ferguson M. Pract Pain Manag. 2022 September/October;22(5). CRPS: A Brief Background Complex regional pain syndrome (CRPS) is a chronic neuro-inflammatory disorder that affects one or more extremities, usually following surgery, injury, or trauma, but also occurs spontaneously. The pathophysiology of CRPS is complex and poorly understood; therefore, well-defined criteria for diagnosis are […]

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Uncategorized Published - 2 December, 2022    By - Dr Clemens
Biased Signaling in G-Protein-Coupled Receptors: The μ Opioid Receptor

Authors: Richard Simoneaux; Steven L. Shafer, MD, FASA ASA Monitor October 2022, Vol. 86, 1–8. In 2012, the Nobel Prize in Chemistry was awarded to Robert J. Lefkowitz, Howard Hughes Medical Institute/Duke University Medical Center, and Brian K. Kobilka, Stanford University School of Medicine, for “groundbreaking discoveries that reveal the inner workings of… G-protein-coupled receptors” (asamonitor.pub/3Cb1vVL). G-protein-coupled […]

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Uncategorized Published - 2 December, 2022    By - Dr Clemens
Bridging the Workforce Gap

#TheAnesthesiaBlog Increasing numbers of NHS consultants are voluntarily reducing their time spent delivering contracted direct clinical care. The result is concerning, with experienced clinicians working less hours and retiring early. This new guidance aims to highlight contributory issues and list clear, implementable solutions. One theme is that ‘age’ in anaesthesia should not be perceived negatively […]

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Uncategorized Published - 1 December, 2022    By - Dr Clemens
Preoperative Ultrasound-guided Percutaneous Cryoneurolysis for the Treatment of Pain after Mastectomy

Authors: Brian M. Ilfeld, M.D., M.S. et al  Anesthesiology November 2022, Vol. 137, 529–542. Background Ultrasound-guided percutaneous cryoneurolysis is an analgesic technique in which a percutaneous probe is used to reversibly ablate a peripheral nerve(s) using exceptionally low temperature, and has yet to be evaluated with randomized, controlled trials. Pain after mastectomy can be difficult to […]

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Uncategorized Published - 1 December, 2022    By - Dr Clemens
THE RISK OF ANESTHESIA PATIENT TRANSPORT

Author: Richard Novak The Anesthesia Consultant Imagine this scenario: You’ve just finished anesthetizing a patient in a hospital setting, and the patient now requires transport from the operating room (OR) to the post-anesthesia care unit (PACU). During surgery your patient monitors included: a pulse oximeter, an ECG, a blood pressure cuff, a temperature monitor, and […]

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