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Anesthesiology Published - 15 September, 2025    By - Dr Clemens
When Blue Dye Turns Skin Blue—Effects of Patent Blue V Administration in Lymphatic Surgery

Authors: Gazzè G, et al. A & A Practice 19(7): e02010, July 2025. doi:10.1213/XAA.0000000000002010 This case report describes a rare adverse reaction to Patent Blue V (PBV), a dye commonly used for lymph node mapping and now increasingly applied in lymphatic reconstruction. A 60-year-old woman undergoing breast reconstruction developed widespread bluish skin discoloration, blue–green urine, […]

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Anesthesiology Published - 12 September, 2025    By - Dr Clemens
Trends in Comorbidities and Complications Among Octogenarians and Nonagenarians Undergoing Primary Total Joint Arthroplasty in the United States

Author: Reisinger Lisa, et al. Anesthesia & Analgesia ():10.1213/ANE.0000000000007631, July 23, 2025. doi:10.1213/ANE.0000000000007631 SummaryReisinger and colleagues analyzed national trends in total knee and hip arthroplasty among octogenarians and nonagenarians using the Premier Healthcare database from 2006–2022. Neuraxial anesthesia was more frequently used in older patients undergoing TKA. While length of stay declined over time across […]

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Anesthesiology Published - 12 September, 2025    By - Dr Clemens
Association of Short-term Pain and Chronic Pain Intensity With Cardiometabolic Multimorbidity Progression

Authors: Chen D, et al. Anesthesia & Analgesia 141(3): 492-501, September 2025. doi:10.1213/ANE.0000000000007228 This UK Biobank prospective cohort study examined the influence of pain intensity on the development and progression of cardiometabolic multimorbidity (CMM). Among 429,145 participants followed for a median of 12.8 years, 13.1% developed an initial cardiometabolic disease (ICMD), 19.6% of those progressed […]

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Anesthesiology Published - 12 September, 2025    By - Dr Clemens
The GABAergic Parafacial Zone: Integrating Consciousness and Respiratory Control in Sevoflurane Anesthesia

Authors: Luo L, et al. Anesthesiology ():10.1097/ALN.0000000000005735, August 28, 2025. doi:10.1097/ALN.0000000000005735 This mouse study investigated whether the parafacial zone (PZ), a GABAergic sleep-promoting region, serves as a common neural node responsible for anesthetic-induced unconsciousness and respiratory depression. By combining chemogenetic and optogenetic approaches, the authors selectively modulated PZ GABAergic neurons and evaluated anesthetic sensitivity, cortical […]

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Anesthesiology Published - 12 September, 2025    By - Dr Clemens
Near-infrared spectroscopy (NIRS) and skin tone in children

Authors: Starnes JR, et al. Anesthesiology ():10.1097/ALN.0000000000005738, August 29, 2025. doi:10.1097/ALN.0000000000005738 This prospective study evaluated the effect of skin tone on near-infrared spectroscopy (NIRS) performance in children undergoing cardiac catheterization. A total of 110 patients under 21 years old were enrolled, with skin tone quantified using spectrophotometry and categorized by individual typology angle (ITA). Forehead […]

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