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Uncategorized Published - 4 April, 2023    By - Dr Clemens
Appropriate Duration of Perioperative Intravenous Administration of Lidocaine to Provide Satisfactory Analgesia for Adult Patients Undergoing Colorectal Surgery 2023

AUTHORS: Yang, Wei MD et al Anesthesia & Analgesia 136(3):p 494-506, March 2023. BACKGROUND: Perioperative lidocaine infusion has been reported to alleviate pain intensity after colorectal surgery. However, there is no consensus on whether prolonged lidocaine infusion is more effective than short lidocaine infusion. This meta-analysis aimed to determine an appropriate duration of lidocaine infusion in […]

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Uncategorized Published - 4 April, 2023    By - Dr Clemens
Postoperative Risk of Transfusion After Reversal of Residual Neuromuscular Block With Sugammadex Versus Neostigmine 2023

AUTHORS: Schmidt, Marc T et al  Anesthesia & Analgesia 136(4):p 745-752, April 2023. BACKGROUND: Sugammadex and neostigmine are routinely used to reverse residual neuromuscular blocks at the end of surgery. Sugammadex has been linked with prolongation of laboratory coagulation markers, but clinical relevance on postoperative blood loss and transfusions remains unclear. METHODS: In this retrospective, single-center, […]

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Uncategorized Published - 4 April, 2023    By - Dr Clemens
Role of Tumor Necrosis Factor Receptor 1—Reactive Oxygen Species—Caspase 11 Pathway in Neuropathic Pain Mediated by HIV gp120 With Morphine in Rats 2023

AUTHORS: Hayashi, Kentaro MD et al  Anesthesia & Analgesia 136(4):p 789-801, April 2023. | BACKGROUND: Recent clinical research suggests that repeated use of opioid pain medications can increase neuropathic pain in people living with human immunodeficiency virus (HIV; PLWH). Therefore, it is significant to elucidate the exact mechanisms of HIV-related chronic pain. HIV infection and chronic morphine […]

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Uncategorized Published - 4 April, 2023    By - Dr Clemens
An updated look at surgically repairing the mitral valve due to mitral regurgitation 2023

Author: Michael Walter Cardiovascular Business Surgically repairing the mitral valve (MV) due to primary mitral regurgitation (MR) is associated with an incredibly low risk of death, according to a new analysis published in both The Annals of Thoracic Surgery and the Journal of the American College of Cardiology.[1,2] The study, a collaboration between cardiologists and cardiothoracic surgeons, was designed to […]

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Uncategorized Published - 3 April, 2023    By - Dr Clemens
Conservative Management of Cervical Radiculopathy 2023

DG Journal Club AUTHORS: Joshua Plener, Ben Csiernik, Daphne To, Sophia da Silva-Oolup Clin J Pain. 2023 Jan 2 OBJECTIVE The purpose of this systematic review is to assess the effectiveness and safety of conservative interventions compared to other interventions, placebo/sham interventions, or no intervention on disability, pain, function, quality of life, and psychological impact in […]

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