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Authors: Sergiy M. Nadtochiy, Ph.D. et al Anesthesiology May 2023, Vol. 138, 523–532. Background Heparin anticoagulation has been used successfully for cardiopulmonary bypass (CPB). However, an alternative anticoagulant approach is desirable due to the cases of heparin-induced thrombocytopenia. Dabigatran provides anticoagulation for an in vitro model of simulated CPB. The current analysis tests the hypothesis that dabigatran provides […]
Read MoreAuthors: Niklas Larsson, M.D. et al Anesthesiology May 2023, Vol. 138, 561–563. To the Editor: Lipid mediators derived from arachidonic acid and other precursor polyunsaturated fatty acids, collectively known as oxylipins, are metabolized along different distinct pathways and play important roles in the modulation of inflammation. Blood oxylipin profiles have been shown to correlate with the survival […]
Read MoreRadius Anesthesia blog Anesthesia is an important part of many medical procedures, especially surgery. While most uses of anesthesia remain uneventful, accidents or mistakes may occur in rare cases, ranging from failing to understand a patient’s medical history to improperly administering anesthesia during a procedure 1. These can result in a wide range of injuries 2. Unintended injuries […]
Read MoreAuthors: Kelly E Michaelsen, MD PhD et al Anesthesiology April 2023. Background Mechanomyography is the traditional gold standard research technique for quantitative assessment of neuromuscular blockade. Mechanomyography directly measures the isometric force generated by the thumb in response to ulnar nerve stimulation. Researchers must construct their own mechanomyographs since commercial instruments are no longer available. […]
Read MoreAuthors: Bettinger J et al Pract Pain Manage. 2023 MayJune:23(2). In this series of analyses, we have broken down the various aspects of the newly released revisions to the CDC Clinical Practice Guideline for Prescribing Opioids for Pain to help clinicians, patients, and caretakers alike understand their nuances and to provide expert review of their applicability, potential […]
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