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Uncategorized Published - 18 January, 2024    By - Dr Clemens
State-related Electroencephalography Microstate Complexity during Propofol- and Esketamine-Induced Unconsciousness

Authors: Zhenhu Liang, Ph.D. et al  Anesthesiology December 2023. Background Identifying the state-related “neural correlates of consciousness” for anesthetics-induced unconsciousness is challenging. Spatiotemporal complexity is a promising tool for investigating consciousness. We hypothesized that spatiotemporal complexity may serve as a state-related but not drug-related EEG indicator during an unconscious state induced by different anesthetic drugs […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
Remimazolam for Intravenous Anesthesia

Radius Anesthesia In July 2020, remimazolam, a novel short-acting drug, was approved in the US for procedural sedation in adults (1). Like midazolam (a common anesthetic adjunct), remimazolam is a benzodiazepine and operates by modulating γ-aminobutyric acid (GABA) receptor activity to induce cell membrane hyperpolarization, thereby inhibiting neural activity via an increase in chloride ion […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
What’s the best way to improve medication adherence in chronic pain management

Author: Morris D, Ferguson M. Ask the PharmD Pract Pain Manag. 2021;21(4). Treatment adherence strategies, including motivational interviewing and case vignettes. Medication adherence is an important part of assessment and disease management, yet it is still difficult for most patients. Nonadherence is linked to hospital admissions, worsehealth outcomes, increased morbidity/mortality, and higher healthcare-related costs. Around […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
The workforce trends scaring physicians

Author: Patsy Newitt Becker’s ASC Review From consolidation to noncompetes, six physician leaders recently joined Becker’s to discuss the workforce trends that are concerning them. Editor’s note: These responses were edited lightly for clarity and length.  Clarissa Arthur, MD. Family Medicine Physician in Nashville, Tenn.: The workforce trend for physicians and providers that is most concerning is that […]

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Uncategorized Published - 18 January, 2024    By - Dr Clemens
Failure of Preclinical Studies to Accurately Predict the Effect of Regional Analgesia on Cancer Recurrence

AUTHORS: Juan P. Cata, M.D.; Daniel I. Sessler, M.D. Anesthesiology January 2024. The major goal of translational research is to evaluate the efficacy and effectiveness of treatments and interventions that have emerged from exhaustive preclinical evidence. In 2007, a major clinical trial was started to investigate the impact of paravertebral analgesia on breast cancer recurrence. The […]

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