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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Mechanically Ventilated Patients With Coronavirus Disease 2019 Had a Higher Chance of In-Hospital Death If Treated With High-Flow Nasal Cannula Oxygen Before Intubation

AUTHORS: Nurok, Michael MBChB, PhD et al  Anesthesia & Analgesia 136(4):p 692-698, April 2023. BACKGROUND: The impact of high-flow nasal cannula (HFNC) on outcomes of patients with respiratory failure from coronavirus disease 2019 (COVID-19) is unknown. We sought to assess whether exposure to HFNC before intubation was associated with successful extubation and in-hospital mortality compared to […]

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Uncategorized Published - 1 August, 2023    By - Dr Clemens
Labor Neuraxial Analgesia and Its Association With Perinatal Outcomes in China in 2015–2016

AUTHORS: Meng, Xi MS et al   Anesthesia & Analgesia March 07, 2023.  BACKGROUND: The use of labor neuraxial analgesia (NA) in China has increased significantly in the past decade, and the current rate of use is unknown. This study aimed to describe the epidemiology of NA based on a large multicenter cross-sectional survey, the China […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Perioperative Iron Deficiency in Patients Scheduled for Major Elective Surgeries

AUTHORS: Capdevila, Xavier MD, PhD et al Anesthesia & Analgesia 137(2):p 322-331, August 2023. BACKGROUND: The management of perioperative iron deficiency is a component of the concept of patient blood management. The objective of this study was to update French data on the prevalence of iron deficiency in patients scheduled for major surgery. METHODS: The CARENFER […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Age-Dependent Electroencephalogram Features in Infants Under Spinal Anesthesia Appear to Mirror Physiologic Sleep in the Developing Brain

AUTHORS: Santa Cruz Mercado et al  Anesthesia & Analgesia March 07, 2023. BACKGROUND: Infants under spinal anesthesia appear to be sedated despite the absence of systemic sedative medications. In this prospective observational study, we investigated the electroencephalogram (EEG) of infants under spinal anesthesia and hypothesized that we would observe EEG features similar to those seen […]

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Uncategorized Published - 31 July, 2023    By - Dr Clemens
Indoleamine 2,3-Dioxygenase Deletion to Modulate Kynurenine Pathway and to Prevent Brain Injury After Cardiac Arrest in Mice

Authors: Aurora Magliocca, MD, PhD et al  Anesthesiology July 2023. Background The catabolism of the essential amino acid tryptophan to kynurenine is emerging as a potential key pathway involved in post-cardiac arrest brain injury. The aim of this study was to evaluate the effects of the modulation of kynurenine pathway on cardiac arrest outcome, through […]

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