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Uncategorized Published - 14 August, 2023    By - Dr Clemens
Manually Controlled, Continuous Infusion of Phenylephrine or Norepinephrine for Maintenance of Blood Pressure and Cardiac Output During Spinal Anesthesia for Cesarean Delivery

AUTHORS: Belin, Olivier MD et al  Anesthesia & Analgesia 136(3):p 540-550, March 2023. BACKGROUND: To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output. We aimed to compare the hemodynamic effects of phenylephrine and norepinephrine administered […]

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Uncategorized Published - 14 August, 2023    By - Dr Clemens
Tracheostomy, Feeding-Tube, and In-Hospital Postoperative Mortality in Children

AUTHORS: Brown, Sydney E. S. MD, PhD et al  Anesthesia & Analgesia 136(6):p 1133-1142, June 2023. BACKGROUND: Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk. Empiric differences between patients with and without these devices and […]

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Uncategorized Published - 14 August, 2023    By - Dr Clemens
Intraoperative Electroencephalography Alpha-Band Power Is a Better Proxy for Preoperative Low MoCA Under Propofol Compared With Sevoflurane

AUTHORS: Guessous, K. MD et al   Anesthesia & Analgesia April 03, 2023. BACKGROUND: Preoperative abnormal cognitive status is a risk factor for postoperative complications yet remains underdiagnosed. During propofol general anesthesia, intraoperative electroencephalography (EEG) variables, such as alpha band power (α-BP), correlate with cognitive status. This relationship under sevoflurane is unclear. We investigated whether […]

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Uncategorized Published - 14 August, 2023    By - Dr Clemens
The Incidence and Predictors of Failed Spinal Anesthesia After Intrathecal Injection of Local Anesthetic for Cesarean Delivery

AUTHORS: Jin, Sherry Y. FRCPC et al  Anesthesia & Analgesia April 03, 2023. BACKGROUND: The incidence of failed spinal anesthesia varies widely in the obstetric literature. Although many risk factors have been suggested, their relative predictive value is unknown. The primary objective of this retrospective cohort study was to determine the incidence of failed spinal […]

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Uncategorized Published - 14 August, 2023    By - Dr Clemens
Restricted Polypharmacy Compared to Usual Care in Mechanically Ventilated Patients

AUTHORS: Bose, Somnath MD, MPH, FASA et al  Anesthesia & Analgesia 136(6):p 1115-1121, June 2023. BACKGROUND: Adverse effects of excessive sedation in critically ill mechanically ventilated patients are well described. Although guidelines strongly recommend minimizing sedative use, additional agents are added as infusions, often empirically. The tradeoffs associated with such decisions remain unclear. METHODS: To test […]

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