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Anesthesiology Published - 18 December, 2025    By - Dr Clemens
Inpatient Cost of Complications After Total Hip and Knee Arthroplasty

Authors: Cozowicz C et al. Anesthesiology, November 2025. DOI: 10.1097/ALN.0000000000005856 SummaryThis large national cohort analysis evaluated economic impacts of major postoperative complications following total hip and knee arthroplasty (THA/TKA). Using the Premier Healthcare database from 2006–2022, the study included more than 2.36 million procedures. Although complications are relatively rare in joint arthroplasty, when they occur […]

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Anesthesiology Published - 18 December, 2025    By - Dr Clemens
Discordances Between Preoperative Creatinine- and Cystatin C-Based Estimated Glomerular Filtration Rate and Outcomes After Noncardiac Surgery

Authors: Lei S-H et al. Anesthesiology, November 2025. DOI: 10.1097/ALN.0000000000005859 SummaryThis large observational cohort study examined whether discrepancies between cystatin C–based and creatinine-based estimated glomerular filtration rate (eGFR) are associated with adverse postoperative outcomes in patients undergoing major noncardiac surgery. The investigators analyzed two geographically distinct Chinese hospital cohorts: 35,488 patients from the Nanfang cohort […]

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Anesthesiology Published - 18 December, 2025    By - Dr Clemens
Nitric Oxide to Reduce Acute Kidney Injury in Patients with Pre-existing Endothelial Dysfunction Requiring Prolonged Cardiopulmonary Bypass

Authors: Arora P et al. Anesthesiology. November 21, 2025. DOI: 10.1097/ALN.0000000000005861 SummaryThis double-blind, placebo-controlled randomized clinical trial evaluated whether inhaled nitric oxide (NO) can reduce postoperative acute kidney injury (AKI) in high-risk cardiac surgery patients with pre-existing endothelial dysfunction. Endothelial dysfunction is marked by impaired endogenous nitric oxide synthesis, and prolonged cardiopulmonary bypass (CPB) increases […]

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Anesthesiology Published - 18 December, 2025    By - Dr Clemens
Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index

Authors: Hussain N et al. Anesthesiology, December 2025. DOI: 10.1097/ALN.0000000000005876 SummarySpinal cord stimulation (SCS) is increasingly used for refractory chronic pain, but the statistical strength of supporting randomized controlled trials (RCTs) has not been well evaluated. This study systematically reviewed 30 RCTs and assessed their fragility index (FI)—the number of events that would need to […]

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Anesthesiology Published - 18 December, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN just increased salary $15,000

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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