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Authors: Laurence Moss, MD et al Anesthesiology September 2023. Background Oliceridine (Olinvyk®) is a μ-opioid receptor agonist that in contrast to conventional opioids preferentially engages the G-protein-coupled signaling pathway. We determined the utility function of oliceridine versus morphine based on neurocognitive tests and cold pressor test. Methods The study had a randomized, double-blind, placebo-controlled, partial block 3-way […]
Read MoreAuthors: Yongchen Cui, M.D. et al Anesthesiology September 2023. Background Continuous nerve block with ropivacaine is commonly performed after repair surgery for traumatic peripheral nerve injuries. After peripheral nerve injury, tetrodotoxin-resistant voltage-gated sodium channel Nav1.8 is upregulated and contributes to macrophage inflammation. We investigated whether ropivacaine promotes peripheral nerve regeneration through Nav1.8-mediated macrophage signaling. Methods […]
Read MoreAuthors: Hyundeok Joo, MD, MAS et al ASA Monitor September 2023, Vol. 87, 1–7. Durable, functionally impactful, and subjectively evident cognitive decline is a feared outcome of anesthesia and surgery, particularly for older adults (Br J Anaesth 2017;118:486-8). We need to look no further than Dr. Daniel Cole, a coauthor of this article and the editor […]
Read MoreAuthor: Avery Hurt Practical Pain Management July 2023 According to the National Council on Aging, older adults make up only 12% of the US population, yet 18% of suicides,1 with chronic pain being a known risk factor for suicide and suicidal behaviors.2 Black older adults (65-plus) are disproportionately affected by the limitations of chronic pain,3 and in addition […]
Read MoreAuthor: John D. Mitchell, MD ASA Monitor September 2023, Vol. 87, 35. As SEA President, I am grateful for the opportunity to share some of our efforts at SEA with the wider ASA community. This post-lockdown period has been one of tremendous growth for our society, fueled by the passion of our members to facilitate excellence […]
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