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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Cognitive Decline and Dementia in Chronic Widespread Pain

Authors: Jiang X. et al. Anesthesiology, October 16, 2025. DOI: 10.1097/ALN.0000000000005731 This large longitudinal population-based study explored whether chronic widespread pain (CWP) contributes to the development of cognitive decline and dementia, using data from nearly 190,000 participants in the UK Biobank with a 13-year follow-up. CWP was defined as self-reported pain across multiple body regions […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Relationship Between V̇A/Q̇ Mismatch and Capnogram Phase III Slope in Acute Bronchoconstriction and Its Modulation by Salbutamol Assessed by Synchrotron Imaging in Rabbit Lung

Authors: Bayat S. et al. Anesthesiology, October 20, 2025. DOI: 10.1097/ALN.0000000000005807 This experimental study investigated how the slope of phase III (SIII) of the volumetric capnogram relates to ventilation–perfusion (V̇A/Q̇) mismatch in acute bronchoconstriction and how this relationship changes after bronchodilator therapy. Using advanced synchrotron radiation K-edge subtraction imaging, the researchers directly visualized and quantified […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Modulation of the Renin–Angiotensin System in Critically Ill Patients: Addressing Seven Key Questions for the Intensivist

Authors: Calabrese A. et al. Anesthesiology, October 20, 2025. DOI: 10.1097/ALN.0000000000005633 This comprehensive review explores how the renin–angiotensin system (RAS) influences the physiology and treatment of critically ill patients, addressing seven key questions relevant to intensivists. The RAS regulates vascular tone, fluid balance, and inflammation through two distinct pathways: the classical ACE/Ang II/AT1R axis (vasoconstrictive, […]

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Anesthesiology Published - 21 October, 2025    By - Dr Clemens
APSF 2000–2025: Transitioning to Perioperative Patient Safety and Reaching Worldwide

Authors: Mark A. Warner, MD; Daniel J. Cole, MD Anesthesia Patient Safety Foundation Vo; 40 No 3 Oct 2025 Summary:Since 2000, the APSF has expanded its focus from anesthesia-specific safety to the broader perioperative setting, while extending its global influence. Building on dramatic safety gains of the late 20th century, the foundation emphasized new priorities, […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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