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Anesthesiology Published - 27 January, 2026    By - Dr Clemens
Pharmacogenomic-Based Oral Morphine Dose Adjustment: Is It Hard to Swallow?

Authors: Henthorn PK et al. Source: Anesthesia & Analgesia, 142(2):274–275, February 2026. SummaryThis editorial examines whether pharmacogenomic information—specifically loss-of-function variants in the drug transporter SLC22A1 (formerly OCT1)—should meaningfully alter how clinicians dose oral morphine. The authors note that anesthesiology has largely avoided drugs requiring genetic dose adjustment by favoring agents with flow-limited metabolism, organ-independent elimination, […]

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Anesthesiology Published - 27 January, 2026    By - Dr Clemens
Site-Specific Blockade of LPA–TRPV1 Interaction at K710 Residue Influences on Myocardial Ischemia/Reperfusion Injury in Ex Vivo Mouse Hearts

Authors: Qile M et al. Source: Anesthesia & Analgesia. January 14, 2026. DOI: 10.1213/ANE.0000000000007907 Summary:Perioperative myocardial ischemia/reperfusion (I/R) injury remains a significant contributor to morbidity and mortality in both cardiac and noncardiac surgery. In this translational mechanistic study, Qile and colleagues investigated the role of lysophosphatidic acid (LPA), a bioactive phospholipid, in mediating myocardial I/R […]

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Anesthesiology Published - 27 January, 2026    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN just increased salary $15,000

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Anesthesiology Published - 27 January, 2026    By - Dr Clemens
Returning to Anesthesia After Burnout, Pain Management, ICU med or administrative job? We Built a Path Back

Burnout or time away in pain, ICU, or administration doesn’t erase your anesthesia training—it just requires a structured path back. For many physicians, it simply means you stepped away to regroup. We work with anesthesiologists every day who want to return to clinical anesthesia after time away in: administration or leadership roles pain medicine critical […]

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Uncategorized Published - 26 January, 2026    By - Dr Clemens
Multimodal Analgesia in Enhanced Recovery After Cardiac Surgery—Does it Work?

Authors: Faloye AO et al. Source: Anesthesia & Analgesia, 142(2):215–218, February 2026. SummaryThis editorial evaluates the role of multimodal analgesia within Enhanced Recovery After Cardiac Surgery (ERACS) pathways in light of a large multicenter retrospective analysis by Kleiman et al using Society of Thoracic Surgeons data. While Enhanced Recovery After Surgery (ERAS) protocols have shown […]

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