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Authors: Sandeep G, Kalbande J V, Gupta A, et al. Cureus June 18, 202416(6): e62621. Abstract Bronchogenic cysts (BCs) are a congenital anomaly, forming fluid-filled sacs in the bronchial tree during fetal development, and are relatively rare in adults. Patients with large BCs in the mediastinum presenting with severe tracheal compression pose a significant challenge […]
Read MoreAuthors: Markus Zadrazil, M.D. et al Anesthesiology July 2024, Vol. 141, 24–31. Background Little is known about the pharmacodynamic characteristics of liposomal bupivacaine. Hypothesizing that they would not identify pharmacodynamic differences from plain bupivacaine during the initial period after administration, but would find better long-term pharmacodynamic characteristics, the authors designed a randomized, controlled, triple-blinded, single-center study […]
Read MoreAuthors: Lena Scotto, MD; Natalie Moreland, MD ASA Monitor March 2024, Vol. 88, 35. Individuals over the age of 65 make up the largest proportion of patients seeking surgical care. Advanced age and underlying cognitive disorders are risk factors for the development of cognitive impairment, the most common complication in this age group. Perioperative neurocognitive disorders (PNDs) […]
Read MoreAuthors: Julie Helms, M.D., Ph.D. et al Anesthesiology July 2024, Vol. 141, 75–86. Background Extracorporeal membrane oxygenation (ECMO) is associated with a high risk of bleeding complications. The specific impact of ECMO on fibrinolysis remains unexplored. The objective of the current pilot observational prospective study was to investigate the longitudinal dynamics of fibrinolytic markers—i.e., changes over […]
Read MoreThe central renin-angiotensin system: A genetic pathway, functional decoding, and selective target engagement characterization in humans. Proc Natl Acad Sci U S A 2024; 121:e2306936121. PMID: 38349873. Author: Charles Emala, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. The peripheral renin angiotensin system (RAS) is a well-characterized hormonal system classically understood to regulate cardiovascular and renal functions, […]
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