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Uncategorized Published - 1 August, 2024    By - Dr Clemens
Endothelium-Derived Extracellular Vesicles Expressing Intercellular Adhesion Molecules Reflect Endothelial Permeability and Sepsis Severity

AUTHORS: Takei, Yusuke MD, PhD et al  Anesthesia & Analgesia 139(2):p 385-396, August 2024. BACKGROUND: Currently, clinical indicators for evaluating endothelial permeability in sepsis are unavailable. Endothelium-derived extracellular vesicles (EDEVs) are emerging as biomarkers of endothelial injury. Platelet endothelial cell adhesion molecule (PECAM) and vascular endothelial (VE)-cadherin are constitutively expressed endothelial intercellular adhesion molecules that regulate […]

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Uncategorized Published - 31 July, 2024    By - Dr Clemens
Determination of the Optimal Volume of 0.5% Ropivacaine in Single-Injection Retroclavicular Brachial Plexus Block for Arthroscopic Shoulder Surgery

Authors: Hongye Zhang, MD et al  Anesthesiology July 2024. Background A brachial plexus block plays an important role in providing perioperative analgesia for shoulder surgery; however, the inherent risk of phrenic nerve block and resulting hemidiaphragmatic paralysis may limit its use in patients with compromised pulmonary function. This study aimed to evaluate safety, efficacy, the […]

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Uncategorized Published - 31 July, 2024    By - Dr Clemens
Accuracy and Precision of Three Acceleromyographs, Three Electromyographs, and a Mechanomyograph Measuring the Train-of-four Ratio in the Absence of Neuromuscular Blocking Drugs

Authors: Zain Wedemeyer, B.S. et al  Anesthesiology August 2024, Vol. 141, 262–271. Background The accuracy and precision of currently available, widely used acceleromyograph and electromyograph neuromuscular blockade monitors have not been well studied. In addition, the normalization of the train-of-four ratio from acceleromyography (train-of-four ratio [T4/T1] divided by the baseline train-of-four ratio) has not been validated […]

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Uncategorized Published - 31 July, 2024    By - Dr Clemens
Decision-making in Perioperative Oliguria: Comment

Authors: Robert G. Hahn, M.D., Ph.D.; Patrick Y. Wuethrich, M.D., Ph.D. Anesthesiology July 2024. To the Editor: We have read the article by Tallarico et al. on perioperative oliguria and congratulate the authors on their well-articulated exploration of this complex topic. We would, however, like to highlight some commonly overlooked aspects. We believe that the diagnostic criteria for […]

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Uncategorized Published - 31 July, 2024    By - Dr Clemens
Decision-making in Perioperative Oliguria: Reply

Authors: Matthieu Legrand, M.D., Ph.D. et al  Anesthesiology July 2024. In Reply: In response to Hahn and Wuethrich’s comment on our article we agree that creatinine-based definitions of acute kidney injury (AKI) are imperfectly specific for damage to kidney tissue, and many such cases of AKI may represent adaptive changes in renal hemodynamics in response to […]

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