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Uncategorized Published - 11 March, 2024    By - Dr Clemens
Intraoperative Trombone Playing during Awake Deep Brain Stimulator Placement

Authors: Whitney Fallahian, M.D.; Stephen Lockwood, M.D. Anesthesiology March 2024, Vol. 140, 585. In this case, a 65-yr-old man with bilateral essential tremor underwent awake deep brain stimulator placement targeted to the ventral intermediate nucleus for symptom management and improved quality of life. The patient’s primary complaint was that the tremor affected his ability to play […]

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Uncategorized Published - 11 March, 2024    By - Dr Clemens
Multicenter, Randomized, Placebo-controlled Crossover Trial Evaluating Topical Lidocaine for Mechanical Cervical Pain

Authors: Steven P. Cohen, M.D. et al  Anesthesiology March 2024, Vol. 140, 513–523. Background There are few efficacious treatments for mechanical neck pain, with controlled trials suggesting efficacy for muscle relaxants and topical nonsteroidal anti-inflammatory drugs. Although studies evaluating topical lidocaine for back pain have been disappointing, the more superficial location of the cervical musculature suggests […]

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Uncategorized Published - 11 March, 2024    By - Dr Clemens
Feasibility of Prone Positioning for Brain-injured Patients with Severe Acute Respiratory Distress Syndrome

Authors: Yoann Elmaleh, M.D. et al  Anesthesiology March 2024, Vol. 140, 495–512. Background Prone position is a key component to treat hypoxemia in patients with severe acute respiratory distress syndrome. However, most studies evaluating it exclude patients with brain injuries without any medical evidence. Methods This study includes a systematic review to determine whether brain-injured patients […]

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Uncategorized Published - 11 March, 2024    By - Dr Clemens
Comparative Analysis of the Performance of Electroencephalogram Parameters for Monitoring the Depth of Sedation During Remimazolam Target-Controlled Infusion

AUTHORS: Bae, Myung Il MD et al  Anesthesia & Analgesia December 05, 2023. BACKGROUND: The changes in hypnotic indicators in remimazolam sedation remain unclear. We investigated the correlation of the electroencephalogram (EEG) parameters with the effect-site remimazolam concentration and the depth of sedation in patients receiving a target-controlled infusion of remimazolam. METHODS: This prospective observational […]

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Uncategorized Published - 11 March, 2024    By - Dr Clemens
Stress Pathways Induced by Volatile Anesthetics and Failure of Preconditioning in a Mitochondrial Complex I Mutant

Authors: Zachariah P. G. Olufs, B.S. et al Anesthesiology March 2024, Vol. 140, 463–482. Background Carriers of mutations in the mitochondrial electron transport chain are at increased risk of anesthetic-induced neurotoxicity. To investigate the neurotoxicity mechanism and to test preconditioning as a protective strategy, this study used a Drosophila melanogaster model of Leigh syndrome. Model flies carried a […]

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