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Authors: Tom van Dasselaar, M.D. et al Anesthesiology March 2024, Vol. 140, 632–633. To the Editor: STR-324 is the chemically stable analog of opiorphin, a human pentapeptide (Gln-Arg-Phe-Ser-Arg), that inhibits two enkephalinases, aminopeptidase-N and neutral endopeptidase. These enkephalinases break down met-enkephalin into inactive metabolites. Both opiorphin and STR-324 are naturally present in humans, because opiorphin rapidly cycles […]
Read MoreAuthors: David R McIlroy, MD et al Anesthesiology February 2024. Background Acute kidney injury (AKI) is common after major abdominal surgery. Selection of candidate kidney protective strategies for testing in large trials should be based on robust preliminary evidence. Methods We conducted a secondary analysis of the Restrictive versus Liberal Fluid Therapy in Major Abdominal […]
Read MoreAuthors: Anthony Tucker-Bartley, M.D. et al Anesthesiology February 2024. We demonstrate a large chest wall hematoma involving the serratus anterior muscle with an extension between the pectoralis major and minor muscles. The images (fig. 1, A–D) are noncontrast chest computed tomography scans in the axial and coronal planes, showing the hematoma, noted 1 day after […]
Read MoreAuthors: Amit K. Saha, Ph.D.; Scott Segal, M.D., M.H.C.M. Anesthesiology March 2024, Vol. 140, 387–398. Background An intraoperative transfer of care from one anesthesia provider to another, or handover, may result in information loss and contribute to adverse patient outcomes. In 2019 the authors undertook a quality improvement effort to increase the use of a structured […]
Read MoreAuthors: Ana Maria Crawford, MD, MSc, FASA; Ninza Sheyo, MBCHB, MPH, FCA (ECSA) ASA Monitor March 2024, Vol. 88, 15–16. Clinical vignette: A 32-year-old female presents to a secondary level hospital with difficult breathing. A nurse assesses vital signs, finding a heart rate of 139 bpm, SpO2 = 71%, respiratory rate at 56 bpm, and temperature of 38.1°C. […]
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