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Uncategorized Published - 24 April, 2024    By - Dr Clemens
Chest Wall Hematoma after Continuous Serratus Anterior Plane Block

Authors: Anthony Tucker-Bartley, M.D. et al  Anesthesiology May 2024, Vol. 140, 1018–1019. We demonstrate a large chest wall hematoma involving the serratus anterior muscle with an extension between the pectoralis major and minor muscles. The images (fig. 1, A–D) are noncontrast chest computed tomography scans in the axial and coronal planes, showing the hematoma, noted 1 […]

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Uncategorized Published - 23 April, 2024    By - Dr Clemens
Serum Neurofilament Light and Postoperative Delirium in Cardiac Surgery

Authors: Céline Khalifa, M.D. et al  Anesthesiology May 2024, Vol. 140, 950–962. Background Impaired cognition is a major predisposing factor for postoperative delirium, but it is not systematically assessed. Anesthesia and surgery may cause postoperative delirium by affecting brain integrity. Neurofilament light in serum reflects axonal injury. Studies evaluating the perioperative course of neurofilament light in […]

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Uncategorized Published - 23 April, 2024    By - Dr Clemens
Electroencephalogram Biomarkers from Anesthesia Induction to Identify Vulnerable Patients at Risk for Postoperative Delirium

Authors: Marie Pollak, M.D. et al  Anesthesiology May 2024, Vol. 140, 979–989. Background Postoperative delirium is a common complication in elderly patients undergoing anesthesia. Even though it is increasingly recognized as an important health issue, the early detection of patients at risk for postoperative delirium remains a challenge. This study aims to identify predictors of postoperative […]

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Uncategorized Published - 23 April, 2024    By - Dr Clemens
Cognitive and Cerebrospinal Fluid Alzheimer’s Disease–related Biomarker Trajectories in Older Surgical Patients and Matched Nonsurgical Controls

Authors: Melody Reese, Ph.D. et al  Anesthesiology May 2024, Vol. 140, 963–978. Background Anesthesia and/or surgery accelerate Alzheimer’s disease pathology and cause memory deficits in animal models, yet there is a lack of prospective data comparing cerebrospinal fluid (CSF) Alzheimer’s disease–related biomarker and cognitive trajectories in older adults who underwent surgery versus those who have not. Thus, the […]

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Uncategorized Published - 23 April, 2024    By - Dr Clemens
Liposomal Bupivacaine’s Plausibility Fails to Translate

Author: Michael R. Fettiplace, M.D., Ph.D. Anesthesiology May 2024, Vol. 140, 868–870. “[As] evidence accumulates, we find that the biologic plausibility of liposomal bupivacaine does not translate into clinical relevance.” For over a century, anesthesiologists have sought to extend the utility, duration, and safety of local anesthetics, from the original topical instillation of cocaine onto the […]

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