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Author: Robert N. Sladen, M.B.Ch.B., M.R.C.P.(U.K.), F.R.C.P.C., F.C.C.M. Anesthesiology May 2024. Background Acute renal dysfunction and subsequent acute renal failure after cardiac surgery are associated with high mortality and morbidity. Early therapeutic or preventive intervention is hampered by the lack of an early biomarker for acute renal injury. Recent studies showed that urinary neutrophil gelatinase–associated […]
Read MoreAuthors: Evangelia Akoumianaki, M.D., Ph.D. et al Anesthesiology May 2024. Background Patient-ventilator dyssynchrony is frequently observed during assisted mechanical ventilation (MV). However, the effects of expiratory muscle contraction on patient-ventilator interaction are underexplored. We hypothesized that active expiration would affect patient-ventilator interaction and we tested our hypothesis in a mixed cohort of invasively ventilated patients […]
Read MoreAuthor: Robert N. Sladen, M.B.Ch.B., M.R.C.P.(U.K.), F.R.C.P.C., F.C.C.M. Anesthesiology May 2024. Background Acute renal dysfunction and subsequent acute renal failure after cardiac surgery are associated with high mortality and morbidity. Early therapeutic or preventive intervention is hampered by the lack of an early biomarker for acute renal injury. Recent studies showed that urinary neutrophil gelatinase–associated […]
Read MoreAuthors: Gamonmas Ekkapat, M.D. et al Anesthesiology May 2024. A 43-yr-old woman experienced acute respiratory failure with right ventricular dysfunction following a complex left pneumonectomy (fig. 1A) with cardiopulmonary bypass. She was intubated and mechanically ventilated. Fig. 1. (A) Chest x-ray showing patchy opacities at the right middle and lower lung zones along with loculated […]
Read MoreAuthors: Kim I. Albers-Warlé, MD et al Anesthesiology May 2024. Background The number of trials investigating the effects of deep neuromuscular blockade (NMB) on surgical conditions and patient outcomes is steadily increasing. Consensus on which surgical procedures benefit from deep NMB (a post tetanic count of 1-2) and how to implement it has not been […]
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