Authors: Brocha Kagan, PA-C KevinMD.com The opioid addiction crisis has escalated into a formidable challenge within the U.S. health care system, causing widespread devastation. The opioid epidemic has not only devastated communities and individual lives but has also inflicted a substantial economic toll on the health care system. The opioid epidemic has led to a […]
Discover The Best Anesthesiologist Opportunity in New Mexico
We are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
Perioperative Naltrexone Management
Authors: Akash Goel, M.D., M.P.H. et al Anesthesiology August 2024, Vol. 141, 388–399. Substance use disorders, including alcohol use disorder, are a public health concern that affect more than 150 million people globally. The opioid antagonist naltrexone is being increasingly prescribed to treat opioid use disorder, alcohol use disorder, and chronic pain. Perioperative management of patients […]
Increased Postoperative Opioid Consumption in the Presence of Coadministration of 5-Hydroxytryptamine Type 3 Antagonists with Acetaminophen
Authors: Nikolai Ratajczak et al Anesthesiology August 2024, Vol. 141, 326–337. Background Acetaminophen and 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists are administered as standard prophylaxes for postoperative pain, nausea, and vomiting. Preclinical studies, however, suggest that 5-HT3 antagonists may compromise acetaminophen’s analgesic effect. This hospital registry study investigates whether 5-HT3 antagonists mitigate the analgesic effect of prophylactic acetaminophen […]
Type II Genial Tubercle Fracture
Authors: Ji Wang, M.D., Ph.D. et al Anesthesiology August 2024, Vol. 141, 375–376. Type II genial tubercle fracture, associated with traumatic mandibular fracture, may cause life-threatening airway compromise. In a case of a 12-yr-old boy with traumatic comminuted mandibular fracture, after anesthesia induction, hypoxia rapidly developed due to a limited view during direct laryngoscopy, intraoral bleeding, […]
Science, Medicine, and the Anesthesiologist
Anesthesiology August 2024, Vol. 141, A13–A15. The subacromial bursa modulates tendon healing after rotator cuff injury in rats. Sci Transl Med 2024; 16:eadd8273. PMID: 38657023. Rotator cuff injuries affect more than 17 million individuals in the United States, leading to approximately 500,000 surgeries each year. These surgeries, which often involve the removal of the subacromial bursa, […]
Anesthesia Blunts Carbon Dioxide Effects on Glymphatic Cerebrospinal Fluid Dynamics in Mechanically Ventilated Rats
Authors: Niklas Daniel Åke Persson, M.Sc. et al Anesthesiology August 2024, Vol. 141, 338–352. Background Impaired glymphatic clearance of cerebral metabolic products and fluids contribute to traumatic and ischemic brain edema and neurodegeneration in preclinical models. Glymphatic perivascular cerebrospinal fluid flow varies between anesthetics possibly due to changes in vasomotor tone and thereby in the dynamics […]
Discover The Best Anesthesiologist Opportunity in New Mexico
We are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
Electroencephalographic Indices for Clinical Endpoints during Propofol Anesthesia in Infants: An Early-phase Propofol Biomarker-finding Study
Authors: Ian Yuan, M.D., M.Eng. et al Anesthesiology August 2024, Vol. 141, 353–364. Background Unlike expired sevoflurane concentration, propofol lacks a biomarker for its brain effect site concentration, leading to dosing imprecision particularly in infants. Electroencephalography monitoring can serve as a biomarker for propofol effect site concentration, yet proprietary electroencephalography indices are not validated in infants. […]
Electrical Impedance Tomography for Assessing the Impact of Inhaled Nitric Oxide on Pulmonary Artery Pressure
Authors: Gamonmas Ekkapat, M.D. et al Anesthesiology August 2024, Vol. 141, 377–378. A 43-yr-old woman experienced acute respiratory failure with right ventricular dysfunction following a complex left pneumonectomy (fig. 1A) with cardiopulmonary bypass. She was intubated and mechanically ventilated. Fig. 1. (A) Chest x-ray showing patchy opacities at the right middle and lower lung zones along […]