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Uncategorized Published - 1 January, 2025    By - Dr Clemens
Happy New Year: A Fresh Start for Everyone!

As the clock strikes midnight and the calendar flips to a brand-new year, we are reminded of the beauty of fresh beginnings. A new year symbolizes hope, opportunity, and the chance to create a better version of ourselves and our world. Whether you’re someone who loves setting resolutions or prefers to take life one day […]

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Anesthesiology Published - 1 January, 2025    By - Dr Clemens
Prophylactic Phenylephrine Boluses Versus Variable Rate Infusion During Elective Cesarean Delivery Under Spinal Anesthesia

Authors: Mohta M et al. Anesthesia & Analgesia. 141(4):736–739, October 2025. SummaryThis randomized, double-blind trial compared prophylactic phenylephrine administered as titrated boluses versus variable-rate infusion for prevention of postspinal hypotension during elective cesarean delivery under spinal anesthesia. While international consensus guidelines recommend prophylactic phenylephrine infusion, infusion pumps may not be universally available, particularly in resource-limited […]

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Anesthesiology Published - 1 January, 2025    By - Dr Clemens
Single Muscle Fibre Calcium Wave Frequency Assay for Malignant Hyperthermia Diagnosis

Authors: Singh DP et al. Anesthesiology. December 2025. SummaryThis exploratory validation study evaluated a novel diagnostic technique for malignant hyperthermia (MH) susceptibility based on direct measurement of calcium release dynamics in single skeletal muscle fibers. The current gold standard for MH diagnosis, the in-vitro contracture test (IVCT), is invasive, resource-intensive, and limited to specialized centers. […]

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Anesthesiology Published - 1 January, 2025    By - Dr Clemens
Changes in intraoperative rocuronium dosing following the introduction of sugammadex and association with postoperative respiratory complications

Authors: Wachtendorf LJ et al. Anesthesiology. December 2025. SummaryThis large retrospective cohort study examined how the introduction of sugammadex influenced intraoperative rocuronium dosing practices and whether changes in dosing were associated with postoperative respiratory complications. While sugammadex enables rapid and reliable reversal of even deep neuromuscular blockade, concerns have emerged that its availability may encourage […]

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Uncategorized Published - 1 January, 2025    By - Dr Clemens
Evaluating Large Language Model Performance in Generating Clinically Relevant Intensive Care Unit Discharge Summaries

Authors: Mudumbai SC et al. A & A Practice. 19(9):e02057, September 2025. SummaryThis study evaluated the clinical quality of large language model (LLM)–generated intensive care unit (ICU) discharge summaries compared with traditional physician-authored summaries. ICU discharge summaries are time-intensive and cognitively demanding, requiring accurate synthesis of complex, longitudinal clinical data. The authors examined whether current […]

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