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Uncategorized Published - 18 June, 2024    By - Dr Clemens
Effects of hemorrhagic shock and rhabdomyolysis on renal microcirculation, oxygenation and function in a female swine model

Authors: Benjamin Bergis, MD, Msc et al  Anesthesiology May 2024. Background Hemorrhagic shock (HS) and rhabdomyolysis (RM) are two important risk factors of acute kidney injury (AKI) after severe trauma, however the effects of the combination of RM and HS on kidney function are unknown. The purpose of this study was to determine the impact […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Combined Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Surgery of the Foot or Ankle

Authors: Mathias Maagaard, M.D. et al  Anesthesiology June 2024, Vol. 140, 1165–1175. Background Both dexamethasone and dexmedetomidine increase the duration of analgesia of peripheral nerve blocks. The authors hypothesized that combined intravenous dexamethasone and intravenous dexmedetomidine would result in a greater duration of analgesia when compared with intravenous dexamethasone alone and placebo. Methods The authors randomly […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Long-term Survival after Volatile or Propofol General Anesthesia for Bladder Cancer Surgery

Authors: Mats Enlund, M.D., Ph.D. et al  Anesthesiology June 2024, Vol. 140, 1126–1133. Background Prospective interventional trials and retrospective observational analyses provide conflicting evidence regarding the relationship between propofol versus inhaled volatile general anesthesia and long-term survival after cancer surgery. Specifically, bladder cancer surgery lacks prospective clinical trial evidence. Methods Data on bladder cancer surgery performed under general […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
Intraoperative Methadone and Postoperative Anesthesia Care Unit Outcomes

Author: Evan D. Kharasch, M.D., Ph.D. Anesthesiology May 2024. To the Editor: Methadone has been used in perioperative anesthesia practice for at least four decades, and there is increasing interest in perioperative methadone use and even more so recently in both inpatients and outpatients.  Intraoperative methadone, compared with short-duration opioids, results in less postoperative opioid […]

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Uncategorized Published - 17 June, 2024    By - Dr Clemens
PROBAST Assessment of Machine Learning: Comment

Authors: Elena Bignami, M.D. et al  Anesthesiology May 2024. To the Editor: We read with interest the article by Arina et al.To our knowledge, it is the most comprehensive and complete review on this topic. As underlined by the authors, the subject is very heterogeneous. For this reason and because data processing is not yet standardized, […]

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