Anesthesiology August 2024, Vol. 141, A13–A15. Coronary sinus reducer for the treatment of refractory angina (ORBITA-COSMIC): A randomised, placebo-controlled trial. Lancet 2024; 403:1543–53. PMID: 38604209. Limited information is available from only canine or single-arm human observational studies for coronary sinus reduction devices, a mesh percutaneously placed in primary venous drainage of the heart as antianginal therapy. […]
Read MoreAuthors: Stephan G. Frangakis, M.D., Ph.D.; Chad M. Brummett, M.D. Anesthesiology August 2024, Vol. 141, 211–213. “[I]n reality patients are spread along a spectrum of severity […], the use of continuous outcomes increases statistical power of a study, allowing for better detection of more subtle clinical effects.” Chronic postsurgical pain (CPSP) remains a significant challenge in healthcare, […]
Read MoreAuthors: Megan E. Salwei, Ph.D. Matthew B. Weinger, M.D., M.S. Anesthesiology August 2024, Vol. 141, 217–221. “This ‘field of dreams’ will quickly become a ‘fire swamp’ if AI is not designed and implemented with a human-centered approach.” Artificial intelligence (AI) is generating widespread enthusiasm due to its potential to transform the way we work and live. […]
Read MoreAnesthesiology September 2024, Vol. 141, A13–A15. A body-brain circuit that regulates body inflammatory responses. Nature 2024; 630:695–703. PMID: 38692285. Previous work has shown the significance of electrical stimulation of the vagal nerve to attenuate inflammation. To decipher how the brain regulates the body’s immune response, activities of neurons in the brain stems of mice were monitored […]
Read MoreAnesthesiology August 2024, Vol. 141, A13–A15. Preoperative GLP-1 receptor agonist use and risk of postoperative respiratory complications. JAMA 2024; 331:1672–3. PMID: 38648036. Current guidance suggests that GLP-1 (glucagon-like peptide 1) receptor agonists be held preoperatively due to an increased risk of pulmonary complications, but large-scale data examining this risk have been missing. This retrospective observational study […]
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