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Uncategorized Published - 22 October, 2025    By - Dr Clemens
General anesthesia and systemic hyperosmolality modulate lumbar intrathecal drug distribution in female rats

Authors: Persson N.D.Å. et al. Anesthesiology, October 9, 2025. DOI: 10.1097/ALN.0000000000005794 This preclinical study examined how anesthesia type and systemic osmotic state influence the central nervous system (CNS) distribution of drugs administered via the lumbar intrathecal route. While intrathecal drug delivery bypasses the blood-brain barrier, it often fails to achieve therapeutic concentrations in the brain, […]

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Uncategorized Published - 22 October, 2025    By - Dr Clemens
BEST Independent CRNA Opportunity – Savannah, TN

Hardin Medical Center (122 beds) is offering a rare CRNA-only practice where you can enjoy full autonomy and an exceptional lifestyle. • Schedule: 2 weeks on / 1 week off (17 weeks off each year)• Model: Independent CRNA practice – no anesthesiologist supervision• Case Mix: General surgery, orthopedics, endoscopy, OB/GYN (including epidurals & C-sections)• No […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Why Anesthesia Billing Deserves More Attention — and How to Decide Between In-House or Outsourced

Authors: Kelley Blair, CEO of nimble,  Caryn Mattia, CPC, Sr. Director of Client Services at nimble Becker’s ASC Review If you run an ASC, you already know how central anesthesia is to your daily operations. Nearly every case — 99% of procedures — requires it. And yet, when I talk with ASC leaders, anesthesia revenue is often the […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Cognitive Decline and Dementia in Chronic Widespread Pain

Authors: Jiang X. et al. Anesthesiology, October 16, 2025. DOI: 10.1097/ALN.0000000000005731 This large longitudinal population-based study explored whether chronic widespread pain (CWP) contributes to the development of cognitive decline and dementia, using data from nearly 190,000 participants in the UK Biobank with a 13-year follow-up. CWP was defined as self-reported pain across multiple body regions […]

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Uncategorized Published - 21 October, 2025    By - Dr Clemens
Relationship Between V̇A/Q̇ Mismatch and Capnogram Phase III Slope in Acute Bronchoconstriction and Its Modulation by Salbutamol Assessed by Synchrotron Imaging in Rabbit Lung

Authors: Bayat S. et al. Anesthesiology, October 20, 2025. DOI: 10.1097/ALN.0000000000005807 This experimental study investigated how the slope of phase III (SIII) of the volumetric capnogram relates to ventilation–perfusion (V̇A/Q̇) mismatch in acute bronchoconstriction and how this relationship changes after bronchodilator therapy. Using advanced synchrotron radiation K-edge subtraction imaging, the researchers directly visualized and quantified […]

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